Browsing by UP Author "Bates, David Owen Bates"

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Alternative splicing events and their clinical significance in colorectal cancer : targeted therapeutic opportunities

Manabile, Mosebo Armstrong; Hull, Rodney; Khanyile, Richard; Molefi, Thulo; Damane, Botle Precious; Mongan, Nigel Patrick; Bates, David Owen Bates; Dlamini, Zodwa (MDPI, 2023-08-07)

Colorectal cancer (CRC) ranks as one of the top causes of cancer mortality worldwide and its incidence is on the rise, particularly in low-middle-income countries (LMICs). There are several factors that contribute to the ...
MicroRNA and alternative mRNA splicing events in cancer drug response/resistance : potent therapeutic targets

Marima, Rahaba; Francies, Flavia Zita; Hull, Rodney; Molefi, Thulo; Oyomno, Meryl; Khanyile, Richard; Mbatha, Sikhumbuzo Z.; Bates, David Owen Bates; Dlamini, Zodwa (MDPI, 2021-12-02)

Cancer is a multifaceted disease that involves several molecular mechanisms including changes in gene expression. Two important processes altered in cancer that lead to changes in gene expression include altered microRNA ...

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