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Browsing by Supervisor "Newton, Claire"
Now showing items 1-6 of 6
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(University of Pretoria, 2022)Sexual development and reproductive function are controlled by the hypothalamic-pituitary-gonadal axis which regulates secretion of luteinising hormone (LH) and follicle stimulating hormone (FSH) which travel through the ...
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(University of Pretoria, 2022)Oxytocin (OXT) and arginine vasopressin (AVP) are well known for their classical roles in initiation of myoepithelial contractions during labour and lactation, and regulation of blood pressure and osmolality, respectively. ...
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(University of Pretoria, 2022)G protein-coupled receptors (GPCRs) are integral membrane proteins, comprising one of the largest gene families. GPCR signalling affects almost all human physiological systems and, as such, the expression of the receptors ...
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(University of Pretoria, 2022)Mutations in G protein-coupled receptors (GPCRs) underlie numerous diseases. Many cause receptor misfolding and failure to reach the cell surface. Pharmacological chaperones are cell-permeant small molecules that engage ...
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(University of Pretoria, 2022)Kisspeptin is a neuropeptide that was first identified as a metastasis suppressor in human melanoma. It is the endogenous ligand for the G protein-coupled receptor, Kisspeptin 1 receptor (KISS1R). In addition to melanoma, ...
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(University of Pretoria, 2022)The ability of cells to communicate constitutes an important characteristic of all multi- cellular organisms. Cells participate in a continuous relay of information between their environment and other cells. These connections ...
Now showing items 1-6 of 6