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Browsing by Supervisor "Maharaj, Vinesh J."
Now showing items 1-13 of 13
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(University of Pretoria, 2023)The great breakthroughs in modern malaria drug discovery and development were a result of studies of medicinal plants used to treat malaria such as Cinchona by the Incas and Artemisia annua by the Chinese. South Africa is ...
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(University of Pretoria, 2022)Two non-daphnane diterpenoids were isolated as biomarkers and later identified using one and two dimensional nuclear magnetic resonance (1D and 2D NMR) as lasioerin and lasiocephalin. The preparative purification of the ...
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(University of Pretoria, 2018)Degradation of elastin and collagen in the extracellular matrix by elastase and collagenase accelerates skin aging. Phytochemicals that inhibit these enzymes can be developed as anti-aging ingredients. The anti-aging ...
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(University of Pretoria, 2015)Medicinal plants and natural products have played a pivotal role as a source of drug leads that has led to improving health conditions and have provided humankind with numerous pharmacologically active drugs. Other than ...
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(University of Pretoria, 2020)Part A of the study focuses on Siphonochilus aethiopicus, also known as African ginger, to determine its antiviral properties and the compounds responsible for the biological activity. African ginger is one of the most ...
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(University of Pretoria, 2013)The plant kingdom contributes significantly to the natural products that are used for the treatment of a large number of ailments and disease across the globe. Included in these species is the Helichrysum genus (Asteraceae), ...
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(University of Pretoria, 2022-05)In this study single solvent system extraction, sequential extraction and supercritical fluid extraction were used to prepare several extracts which were initially selectively investigated for their inhibition of selected ...
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(University of Pretoria, 2019)Ancistrocladus is the only genus in the Ancistrocladaceae family and together with the closely related Dioncophyllaceae, they produce naphthylisoquinoline (NIQ) alkaloids. This class of compounds exhibits a very interesting ...
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(University of Pretoria, 2009)From the Helichrysum genus 600 species occur in Africa of which 244 species are found in South Africa. The most commonly used Helichrysum species for medicinal purposes are H. cymosum, H. odoratissimum, H. petiolare and ...
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(University of Pretoria, 2019-12)Fifteen naphthylisoquinoline (NIQ) alkaloids including four new compounds, the 5,8'-coupled ancistroyafungines A-C, and the 5,1'-linked ancistroyafungine D, as well as eleven known NIQs were isolated from the stem bark of ...
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(University of Pretoria, 2019-03-01)Alzheimer’s disease is a slow and progressive neurodegenerative disease that destroys memory and other important mental functions. APP (Amyloid precursor protein) is an integral membrane protein expressed in higher levels ...
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(University of Pretoria, 2021)In South Africa there are regular cases of human and animal poisoning where plants used in ethnic medicine are suspected to be the source of the poison. This project aims to develop methods for identifying and quantifying ...
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(University of Pretoria, 2008-08-19)The process of investigating plants to identify chemical substances is of great interest to natural product scientists because there is a need to discover new drugs for treating diseases. In our study, plant extracts were ...
Now showing items 1-13 of 13