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Browsing by Supervisor "Anderson, Ross"
Now showing items 1-6 of 6
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(University of Pretoria, 2023-03-03)The recent advancements in gene editing have provided scientists with a powerful tool for the investigation of the role of individual proteins in cellular physiology and disease. Gene editing was preceded by another powerful ...
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(University of Pretoria, 2022)Oxytocin (OXT) and arginine vasopressin (AVP) are well known for their classical roles in initiation of myoepithelial contractions during labour and lactation, and regulation of blood pressure and osmolality, respectively. ...
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(University of Pretoria, 2022)G protein-coupled receptors (GPCRs) are integral membrane proteins, comprising one of the largest gene families. GPCR signalling affects almost all human physiological systems and, as such, the expression of the receptors ...
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(University of Pretoria, 2022)Mutations in G protein-coupled receptors (GPCRs) underlie numerous diseases. Many cause receptor misfolding and failure to reach the cell surface. Pharmacological chaperones are cell-permeant small molecules that engage ...
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(University of Pretoria, 2010)The major cause of HIV-related mortality in Sub-Saharan countries is pulmonary tuberculosis (TB), which is an escalating threat due to the emergence of multidrug resistant (MDR) and extremely multidrug resistant (XDR) TB. ...
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(University of Pretoria, 2021-02-10)Kisspeptin receptor, also known as KISS1R, is the endogenous receptor for the ligand peptide, kisspeptin. It is a G-protein coupled receptor that couples through the Gαq/11 pathway. It has been shown that KISS1R activation ...
Now showing items 1-6 of 6