Browsing by Subject "S-adenosyl-L-methionine decarboxylase"

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Novel S-adenosyl-L-methionine decarboxylase inhibitors as potent antiproliferative agents against intraerythrocytic Plasmodium falciparum parasites

Le Roux, Dina; Burger, Pieter Buys; Niemand, Jandeli; Grobler, Anne; Urbán, Patricia; Fernàndez-Busquets, Xavier; Barker, Robert H.; Serrano, Adelfa; Louw, Abraham Izak; Birkholtz, Lyn-Marie (Elsevier, 2014-04)

S-adenosyl-L-methionine decarboxylase (AdoMetDC) in the polyamine biosynthesis pathway has been identified as a suitable drug target in Plasmodium falciparum parasites, which causes the most lethal form of malaria. ...

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