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Browsing by Subject "Quinolinic acid"
Now showing items 1-5 of 5
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(Wiley, 2023-10)The metastatic behavior of melanoma has accentuated the need for specific therapy targets. Compounds, namely L‐kynurenine (L‐kyn), quinolinic acid (Quin), and kynurenic acid (KA) previously displayed antiproliferative ...
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(Wiley, 2022-08)Cancer is the second leading cause of mortality worldwide. Skin cancer is the most common cancer in South Africa with nearly 20,000 reported cases every year and 700 deaths. If diagnosed early, the 5‐year survival rate ...
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(VYT, 2022)Melanoma is the leading cause of death from skin cancer, due to its ability to metastasise (spread). In my study, I tested two compounds, namely L-kynurenine and quinolinic acid on melanoma cells. It was found that both ...
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Newly developed method for quantification of tryptophan and its metabolites : clinical application (2008-11-12)Tryptophan, an essential amino acid, follows important metabolic pathways for protein, niacin and serotonin synthesis. The kynurenine pathway is a major pathway for tryptophan degradation. Indications are that tryptophan ...
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(University of Pretoria, 2008-04-29)Tryptophan is metabolised along the kynurenine pathway under the influence of tryptophan 2,3 dioxygenase and indoleamine 2,3 dioxygenase. Quinolinic acid and kynurenine, two neuroactive metabolites of the kynurenine pathway ...
Now showing items 1-5 of 5