Browsing by Subject "Peptide nucleic acid"

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Laboratory Detection and Gene Cassette Stability of the Novel Extended-Spectrum Beta-Lactamase, GES-2 from Pseudomonas aeruginosa

Weldhagen, Gerhard Frederick (University of Pretoria, 2004)

Extended-spectrum beta-lactamases (ESBLs) in Pseudomonas aeruginosa tend to be geographically scattered, such as GES-2, which partially compromises the efficacy of imipenem. The G170N mutation, ascribed to a CC to AA base ...
Rapid detection of GES-type extended-spectrum β-lactamases in Pseudomonas aeruginosa with a peptide nucleic acid-based realtime PCR assay

Labuschagne, Christiaan De Jager (University of Pretoria, 2008-09-25)

Extended-spectrum β-lactamases (ESBLs) constitute a major problem given their broad substrate specificity and ability to hydrolyse many of the extended-spectrum third-generation cephalosporins currently in use in hospital ...

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