Browsing by Subject "Life cycle stages"

Browsing by Subject "Life cycle stages"

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  • Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box 
    Reader, Janette; Van der Watt, Mariette Elizabeth; Taylor, Dale; Le Manach, Claire; Mittal, Nimisha; Ottilie, Sabine; Theron, Anjo; Moyo, Phanankosi; Erlank, Erica; Nardini, Luisa; Venter, Nelius; Lauterbach, Sonja; Bezuidenhout, Belinda; Horatscheck, Andre; Van Heerden, Ashleigh; Spillman, Natalie J.; Cowell, Anne N.; Connacher, Jessica I.; Opperman, Daniel; Orchard, Lindsey M.; Llinas, Manuel; Istvan, Eva S.; Goldberg, Daniel E.; Boyle, Grant A.; Calvo, David; Mancama, Dalu; Coetzer, Theresa L.; Winzeler, Elizabeth A.; Duffy, James; Koekemoer, Lizette L.; Basarab, Gregory; Chibale, Kelly; Birkholtz, Lyn-Marie (Nature Publishing Group, 2021-01)
    Chemical matter is needed to target the divergent biology associated with the different life cycle stages of Plasmodium. Here, we report the parallel de novo screening of the Medicines for Malaria Venture (MMV) Pandemic ...