Browsing by Author "Malahleha, Mookho"

Browsing by Author "Malahleha, Mookho"

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  • Addressing missed visits to improve retention of young South African women in clinical trials 
    Ahmed, Khatija; Malahleha, Mookho; Mbatsane, Thulisile E.; Thindisa, Dineo; Bailey, Veronique C.; Seocharan, Ishen; Dilraj, Athmanundh (Academy of Science of South Africa, 2023-07)
    In clinical trials, a vital protocol requirement for participants is adherence to scheduled visits. A substantial number of missed visits and the resultant missing data could affect generalisability of the findings ...
  • Exploring a community’s understanding of HIV vaccine‑induced seropositivity in a South African research setting 
    Malahleha, Mookho; Dilraj, A.; Jean, J.; Morar, N.S.; Dietrich, J.J.; Ross, M.; Mbatsane, E.; Keefer, M.C.; Ahmedm, K. (Health and Medical Publishing Group, 2022-01)
    BACKGROUND. The high HIV prevalence and incidence in South Africa makes it suitable for recruitment of participants for large-scale HIV preventive vaccine trials. However, fear of vaccine-induced seropositivity (VISP) may ...
  • Incorporating oral PrEP into standard prevention services for South African women : a nested interrupted time-series study 
    Donnell, Deborah; Beesham, Ivana; Welch, Julia D.; Heffron, Renee; Pleaner, Melanie; Kidoguchi, Lara; Palanee-Phillips, Thesla; Ahmed, Khatija; Baron, Deborah; Bukusi, Elizabeth A.; Louw, Cheryl; Mastro, Timothy D.; Smit, Jennifer; Batting, Joanne R.; Malahleha, Mookho; Bailey, Veronique C.; Beksinska, Mags; Rees, Helen; Baeten, Jared M. (Elsevier, 2021-08)
    BACKGROUND : As oral pre-exposure prophylaxis (PrEP) becomes the standard of prevention globally, its potential effect on HIV incidence in clinical trials of new prevention interventions is unknown, particularly for trials ...
  • Integrating oral PrEP delivery among African women in a large HIV endpoint-driven clinical trial 
    Beesham, Ivana; Welch, Julia D.; Heffron, Renee; Pleaner, Melanie; Kidoguchi, Lara; Palanee-Phillips, Thesla; Ahmed, Khatija; Baron, Deborah; Bukusi, Elizabeth A.; Louw, Cheryl; Mastro, Timothy D.; Smit, Jennifer; Batting, Joanne R.; Malahleha, Mookho; Bailey, Veronique C.; Beksinska, Mags; Donnell, Deborah; Baeten, Jared M. (Wiley Open Access, 2020-05)
    INTRODUCTION : Global guidelines emphasize the ethical obligation of investigators to help participants in HIV-endpoint trials reduce HIV risk by offering an optimal HIV prevention package. Oral pre-exposure prophylaxis ...
  • Vaccine efficacy of ALVAC-HIV and bivalent subtype C gp120–MF59 in adults 
    Gray, Glenda E.; Bekker, Linda‑Gail; Laher, Fatima; Malahleha, Mookho; Allen, Mary; Moodie, Zoe; Grunenberg, Nicole; Huang, Yunda; Grove, Doug; Prigmore, Brittany; Kee, Jia J.; Benkeser, David; Hural, John; Innes, Craig; Lazarus, Erica; Meintjes, Graeme; Naicker, Nivashnee; Kalonji, Dishiki; Nchabeleng, Maphoshane; Sebe, Modulakgotla; Singh, Nishanta; Kotze, Philip; Kassim, Sheetal; Dubula, Thozama; Naicker, Vimla; Brumskine, William; Ncayiya, Cleon N.; Ward, Amy M.; Garrett, Nigel; Kistnasami, Girisha; Gaffoor, Zakir; Selepe, Pearl; Makhoba, Philisiwe B.; Mathebula, Matsontso P.; Mda, Pamela; Adonis, Tania; Mapetla, Katlego S.; Modibedi, Bontle; Philip, Tricia; Kobane, Gladys; Bentley, Carter; Ramirez, Shelly; Takuva, Simbarashe G.; Jones, Megan; Sikhosana, Mpho; Atujuna, Millicent; Andrasik, Michele; Hejazi, Nima S.; Puren, Adrian; Wiesner, Lubbe; Phogat, Sanjay; Granados, Carlos Diaz; Koutsoukos, Marguerite; Van Der Meeren, Olivier; Barnett, Susan W.; Kanesa‑Thasan, Niranjan; Kublin, James G.; McElrath, Juliana; Gilbert, Peter B.; Janes, Holly; Corey, Lawrence (Massachusetts Medical Society, 2021-03-25)
    BACKGROUND : A safe, effective vaccine is essential to eradicating human immunodeficiency virus (HIV) infection. A canarypox–protein HIV vaccine regimen (ALVAC-HIV plus AIDSVAX B/E) showed modest efficacy in reducing ...