Browsing by UP Author "De Jager, Christiaan"

Browsing by UP Author "De Jager, Christiaan"

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  • Increased caspase-3-dependent spermatogenic cell death and dysregulated adult spermatogenesis following in utero, lactational and direct exposure to para-nonylphenol 
    De Jager, Christiaan; Bornman, Maria S. (Riana); McClusky, Leon M. (Elsevier, 2006-09-20)
  • Malaria research and its influence on antimalarial drug policy in Malawi : a case study 
    Mwendera, Chikondi; De Jager, Christiaan; Longwe, Herbert; Phiri, Kamija; Hongoro, Charles; Mutero, Clifford Maina (BioMed Central, 2016-06-01)
    BACKGROUND : In 1993, Malawi changed its first-line anti-malarial treatment for uncomplicated malaria from chloroquine to sulfadoxine-pyrimethamine (SP), and in 2007, it changed from SP to lumefantrine-artemether. The ...
  • Malaria research in Malawi from 1984 to 2016 : a literature review and bibliometric analysis 
    Mwendera, Chikondi; De Jager, Christiaan; Longwe, Herbert; Hongoro, Charles; Mutero, Clifford Maina; Phiri, Kamija S. (BioMed Central, 2017-06-12)
    BACKGROUND : Malaria research can play a vital role in addressing the malaria burden in Malawi. An organized approach in addressing malaria in Malawi started in 1984 by the establishment of the first National Malaria ...
  • Malaria vectors and vector surveillance in Limpopo Province (South Africa) : 1927 to 2018 
    Braack, L.E.O.; Bornman, Maria S. (Riana); Kruger, Taneshka; Dahan-Moss, Yael; Gilbert, Allison; Kaiser, Maria; Oliver, Shuné V.; Cornel, Anthony J.; Lee, Yoosook; Norris, Douglas E.; Brooke, Basil; Coetzee, Maureen; De Jager, Christiaan (MDPI Publishing, 2020-06-09)
    Despite the annual implementation of a robust and extensive indoor residual spraying programme against malaria vectors in Limpopo Province (South Africa), significant transmission continues and is a serious impediment ...
  • Morbidity and mortality due to malaria in Est Mono district, Togo, from 2005 to 2010 : a times series analysis 
    Landoh, Essoya D.; Tchamdja, Potougnima; Saka, Bayaki; Tint, Khin-San; Gitta, Sheba N.; Wasswa, Peter; De Jager, Christiaan (BioMed Central, 2013-11-23)
    BACKGROUND: In 2004, Togo adopted a regional strategy for malaria control that made use of insecticide-treated nets (ITNs), followed by the use of rapid diagnostic tests (RDTs), artemisinin-based combination therapy ...
  • Mosquito community composition in South Africa and some neighboring countries 
    Cornel, Anthony J.; Lee, Yoosook; De Almeida, Antonio Paulo Gouveia; Johnson, Todd; Mouatcho, Joel Claude; Venter, Marietjie; De Jager, Christiaan; Braack, L.E.O. (BioMed Central, 2018)
    BACKGROUND : A century of studies have described particular aspects of relatively few mosquito species in southern Africa, mostly those species involved with disease transmission, specifically malaria and arboviruses. ...
  • Mosquito-borne arboviruses of African origin : review of key viruses and vectors 
    Braack, L.E.O.; De Almeida, Antonio Paulo Gouveia; Cornel, Anthony J.; Swanepoel, Robert; De Jager, Christiaan (BioMed Central, 2018-01-09)
    Key aspects of 36 mosquito-borne arboviruses indigenous to Africa are summarized, including lesser or poorly-known viruses which, like Zika, may have the potential to escape current sylvatic cycling to achieve greater ...
  • Oestrogenic activity in drinking waters from a rural area in the Waterberg District, Limpopo Province, South Africa 
    Aneck-Hahn, Natalie Hildegard; Bornman, Maria S. (Riana); De Jager, Christiaan (Water Research Council, 2009-04)
    In South Africa, limited data are available regarding possible oestrogenic activity in the aquatic systems and especially drinking water. Water in the rural areas is often contaminated with a complex mixture of toxic ...
  • Oestrogenicity and chemical target analysis of water from small-sized industries in Pretoria, South Africa 
    Mahomed, Shenaaz Ismail; Voyi, K.V.V. (Kuku); Aneck-Hahn, Natalie Hildegard; De Jager, Christiaan (Water Research Council, 2008)
    Increasing concern about endocrine disrupting chemicals (EDCs) and their effects on humans, animals and the environment resulted in this study being conducted. Water from 7 sites in the Pretoria West area (South Africa), ...
  • Pesticide residues and estrogenic activity in fruit and vegetables sampled from major fresh produce markets in South Africa 
    Mutengwe, Mbulaheni Thomas; Aneck-Hahn, Natalie Hildegard; Korsten, Lise; Van Zijl, Magdalena Catherina; De Jager, Christiaan (Taylor and Francis, 2016)
    Food is likely to be one of the major pathways through which people are exposed to endocrinedisrupting chemicals. With the exception of residual effects, there are concerns that a number of naturally occurring and synthetic ...
  • The Pine river statement : human health consequences of DDT use 
    Eskenazi, Brenda; Chevrier, Jonathan; Rosas, Lisa Goldman; Anderson, Henry A.; Bornman, Maria S. (Riana); Bouwman, Henk; Chen, Aimin; Cohn, Barbara A.; De Jager, Christiaan; Henshel, Diane S.; Leipzig, Felicia; Leipzig, John S.; Lorenz, Edward C.; Snedeker, Suzanne M.; Stapleton, Darwin (National Institute of Environmental Health Sciences (NIEHS), 2009-09)
    OBJECTIVES: Dichlorodiphenyltrichloroethane (DDT) was used worldwide until the 1970s, when concerns about its toxic effects, its environmental persistence, and its concentration in the food supply led to use restrictions ...
  • Predicting malaria cases using remotely sensed environmental variables in Nkomazi, South Africa 
    Adeola, Abiodun Morakinyo; Botai, Joel Ongego; Olwoch, Jane Mukarugwiza; Rautenbach, Cornelis Johannes de Wet; Adisa, O.M. (Omolola); De Jager, Christiaan; Botai, Mihloti Christina; Mabuza, Aaron (PAGEpress, 2019)
    There has been a conspicuous increase in malaria cases since 2016/2017 over the three malaria-endemic provinces of South Africa. This increase has been linked to climatic and environmental factors. In the absence of ...
  • Simultaneous exposure to low concentrations of dichlorodiphenyltrichloroethane, deltamethrin, nonylphenol and phytoestrogens has negative effects on the reproductive parameters in male Spraque-Dawley rats 
    Kilian, Elmare; Delport, Rhena; Bornman, Maria S. (Riana); De Jager, Christiaan (Blackwell, 2007-08)
    Many reports suggest that male reproductive health has deteriorated over the last decades, possibly due to environmental contaminants that act as endocrine disruptors. This hypothesis was tested in Sprague-Dawley rats ...
  • Sperm chromatin integrity in DDT-exposed young men living in a malaria area in the Limpopo Province, South Africa 
    De Jager, Christiaan; Aneck-Hahn, Natalie Hildegard; Bornman, Maria S. (Riana); Farias, Paulina; Leter, G.; Eleuteri, P.; Rescia, M.; Spanò, M. (Oxford University Press, 2009-07)
    There is mounting evidence that deteriorated semen quality may be associated with increased serum concentration of 1,1,1-trichloro-2,2-bis(chlorodiphenyl)ethane (DDT) and its metabolites. The problem is exacerbated in ...
  • Stage-related increase in the proportion of apoptotic germ cells and altered frequencies of stages in the spermatogenic cycle following gestational, lactational, and direct exposure of male rats to p-nonylphenol 
    McClusky, Leon M.; De Jager, Christiaan; Bornman, Maria S. (Riana) (Oxford University Press, 2007-01)
    The cumulative effects of environmental toxicants, for example, the alkylphenol, para-nonylphenol (p-NP) are of concern. Our previous study showed that p-NP reduced several testicular morphometric parameters, including ...
  • Standards in semen examination : publishing reproducible and reliable data based on high-quality methodology 
    Bjorndahl, Lars; Barratt, Christopher L.R.; Mortimer, David; Agarwal, Ashok; Aitken, Robert J.; Alvarez, Juan G.; Aneck-Hahn, Natalie Hildegard; Arver, Stefan; Baldi, Elisabetta; Bassas, Lluis; Boitrelle, Florence; Bornman, Maria S. (Riana); Carrell, Douglas T.; Castilla, Jose A.; Cerezo Parra; Parra, Gerardo Cerezo; Check, Jerome H.; Cuasnicu, Patricia S.; Darney, Sally Perreault; De Jager, Christiaan; De Jonge, Christopher J.; Drevet, Joel R.; Drobnis, Erma Z.; Du Plessis, Stefan S.; Eisenberg, Michael L.; Esteves, Sandro C.; Evgeni, Evangelini A.; Ferlin, Alberto; Garrido, Nicolas; Giwercman, Aleksander; Goovaerts, Ilse G.F.; Haugen, Trine B.; Henkel, Ralf; Henningsohn, Lars; Hofmann, Marie-Claude; Hotaling, James M.; Jedrzejczak, Piotr; Jouannet, Pierre; Jorgensen, Niels; Kirkman Brown, Jackson C.; Krausz, Csilla; Kurpisz, Maciej; Kvist, Ulrik; Lamb, Dolores J.; Levine, Hagai; Loveland, Kate L.; McLachlan, Robert, I.; Mahran, Ali; Maree, Liana; Da Silva, Sarah Martins; Mbizvo, Michael T.; Meinhardt, Andreas; Menkveld, Roelof; Mortimer, Sharon T.; Moskovtsev, Sergey; Muller, Charles H.; Jose Munuce, Maria; Muratori, Monica; Niederberger, Craig; O'Flaherty, Cristian; Oliva, Rafael; Ombelet, Willem; Pacey, Allan A.; Palladino, Michael A.; Ramasamy, Ranjith; Ramos, Liliana; Rives, Nathalie; Roldan, Eduardo Rs; Rothmann, Susan; Sakkas, Denny; Salonia, Andrea; Sanchez-Pozo, Maria Cristina; Sapiro, Rosanna; Schlatt, Stefan; Schlegel, Peter N.; Schuppe, Hans-Christian; Shah, Rupin; Skakkebaek, Niels E.; Teerds, Katja; Toskin, Igor; Tournaye, Herman; Turek, Paul J.; Van der Horst, Gerhard; Vazquez-Levin, Monica; Wang, Christina; Wetzels, Alex; Zeginiadou, Theodosia; Zini, Armand (Oxford University Press, 2022-10)
    Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen ...
  • Successfully controlling malaria in South Africa 
    Moonasar, Devanand; Raman, Jaishree; Morris, Neil Kenneth; Ukpe, I.S. (Indongesit Sunday); Maharaj, Rajendra; De Jager, Christiaan; Blumberg, Lucille Hellen; Frean, J.; Asomugha, Chika; Baker, Lee; Barnes, K.I.; Brooke, Basil D.; Coetzee, M.; Duvenage, C.; Groepe, M.A.; Kleinschmidt, I.; Koekemoer, Lizette L.; Kruger, P.; Mabuza, A.; Margo, B.; Mayet, N.T.; Misiani, Eunice; Mokate, R.; Raswiswi, E. (Health and Medical Publishing Group, 2014-03)
    Following major successes in malaria control over the past 75 years, South Africa is now embarking on a malaria elimination campaign with the goal of zero local transmission by the year 2018. The key control elements have ...
  • Sustainable malaria control : transdisciplinary approaches for translational applications 
    Birkholtz, Lyn-Marie; Bornman, Maria S. (Riana); Focke, Walter Wilhelm; Mutero, Clifford Maina; De Jager, Christiaan (BioMed Central, 2012-12-20)
    With the adoption of the Global Malaria Action Plan, several countries are moving from malaria control towards elimination and eradication. However, the sustainability of some of the approaches taken may be questionable. Here, ...
  • Testicular microlithiasis and neoplastic lesions in wild eland (Tragelaphus oryx) : possible effects of exposure to environmental pollutants? 
    Bornman, Maria S. (Riana); Barnhoorn, Irene E.J.; De Jager, Christiaan; Veeramachaneni, D.N.R. (Elsevier, 2010-05)
    The purpose of the study was to compare wildlife in the proximity and away from the sources of known industrial pollution. Macroscopic, focal, gritty areas that appeared white were observed in the testes of all 24 South ...
  • Veterinary growth promoters in cattle feedlot runoff : estrogenic activity and potential effects on the rat male reproductive system 
    Patrick, Sean Mark; Aneck-Hahn, Natalie Hildegard; Van Wyk, Susan; Van Zijl, Magdelena Catherina; Huma, Mampedi; De Jager, Christiaan (Springer, 2020-04)
    The contribution of veterinary growth promoters (VGP) to the environmental burden of endocrine-disrupting chemicals (EDCs) is largely unknown. At cattle feedlots, the excrement of cattle may contain VGPs, which can contaminate ...