Recent Submissions

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    Prevalence of depressive and generalized anxiety features among patients with chronic care conditions
    Phaahla, R. Dorothy; Musekiwa, Alfred (Taylor and Francis, 2026)
    BACKGROUND : Mental illness remains a major public health concern globally. Patients with chronic conditions are vulnerable. OBJECTIVES : The study determined the proportion and associated factors of depression and anxiety among patients with chronic conditions, as it explores the implications for integrated mental healthcare delivery, by determining the prevalence of depressive and generalized anxiety features among patients receiving chronic care. Exploring how the coexistence of chronic physical illness and psychological distress may inform strategies for integrated, patient-centred care within primary healthcare settings. METHODS : Cross-sectional study of adult patients receiving chronic care. A PHQ-9 score of ≥10 indicated positive screening for depression and a GAD-7 score of ≥10 indicated anxiety. Multivariable logistic regression analysis was applied. RESULTS : Out of 286 patients, 30.4%(n = 87) were treated for hypertension and 26.9%(n = 77) for HIV. Depression was positively screened in 60.5%(n = 173) and anxiety in 66.1%(n = 189) patients. The odds of screening positive for depression were higher among patients with diabetes (aOR 1.92, 95%CI: 1.0-3.7), TB(aOR 3.66, 95%CI: 1.4-9.5). Positive screening for anxiety was higher among female residents. CONCLUSION : High rates of undiagnosed depression and anxiety are present in patients with chronic care conditions.
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    Prevalence and genetic diversity of Haemoproteus and Leucocytozoon in raptors and other captive birds at the National Zoological Garden in South Africa
    Gaorekwe, Realeboga Masego; Phetla, Veronica; Malatji, Dikeledi Petunia; Chaisi, Mamohale E. (Wiley, 2026-01)
    Avian haemosporidian infections have been associated with disease outbreaks in zoos and rehabilitation centers globally. This study aimed to determine the occurrence and genetic diversity of avian haemosporidian parasites in captive birds at the National Zoological Garden in South Africa. One hundred and eighty-three blood samples from five orders and 15 species of captive flamingos, vultures, owls, ibises and parrots were analyzed for haemosporidia by nested polymerase chain reaction assays. The samples were collected as part of the zoo's studbook and archived at South African National Biodiversity Institute's Wildlife Biobank. The overall infection rate was 36.1%, and infections by Leucocytozoon spp. (33.3%) were significantly higher than Haemoproteus spp. (14.8%) (p < 0.001). Twenty-one samples (11.5%) had mixed Haemoproteus and Leucocytozoon infections. The Spotted Eagle Owl (Bubo africanus) and Barn Owl (Tyto alba) had the highest infection rates. Twenty-six sequences, similar to published sequences of Leucocytozoon spp. (lineages lCHRKLA02, lCIAE02, and lBUVIR02) and Haemoproteus spp. (lineage hTYTAL6) were obtained. Two new lineages (lBUBCAP01 and hBOSHAG02) are described in this study. This is the first molecular survey of haemosporidian parasites in captive birds of the orders Accipitriformes, Pelecaniformes, Psittaciformes, Phoenicopteriformes, and Strigiformes in South Africa. This study provides new geographical and host records of known and novel haemosporidian lineages. It highlights the need for intensive surveys of these parasites in populations of captive and free-ranging birds in South Africa, regular monitoring of infections, updated screening methods, and insect control in the zoo's animal collection to avoid disease outbreaks.
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    Prevalence and determinants of time to first intimate partner violence incidents among ever-married Ethiopian women
    Mengste, Ashefet Agete; Belay, Denekew Bitew; Fenta, Haile Mekonnen; Chen, Ding-Geng (Din) (Elsevier, 2026-03)
    BACKGROUND : Intimate partner violence (IPV), including physical, emotional, and sexual abuse disproportionately affects women globally, particularly in sub-Saharan Africa. OBJECTIVE : This study examined the timing and determinants of first experiences of IPV among ever-married Ethiopian women. PARTICIPANTS AND SETTING : The study analyzed nationally representative data from 4720 ever-married women who participated in the 2016 Ethiopian Demographic and Health Survey. METHODS : Cox proportional hazards and parametric accelerated failure time (AFT) models were used to identify factors influencing time to first IPV. Women who had not experienced IPV by the survey date or who reported IPV occurring before marriage were treated as right-censored. Multiple AFT distributions were compared, and the best-fitting models were selected. RESULTS : Approximately 30 % of women reported experiencing at least one form IPV, most commonly emotional (22.3 %). The log-normal AFT model best fit physical and sexual violence, while the Weibull AFT model fit emotional violence. Older women (35–49 years) experienced IPV later than younger women (time ratios [TR]: 2.09 physical, 2.82 sexual, 3.00 emotional). Husband's alcohol use, controlling behavior, family violence history, and fear of the husband were associated with earlier IPV occurrence (TR < 1). More children delayed physical and emotional violence (TR > 1), while older age at marriage predicted earlier emotional violence (TR = 0.7). CONCLUSIONS : Age, regional differences, family background, and husbands' behaviors significantly influence the timing of IPV onset among Ethiopian women. Targeted prevention programs addressing harmful partner behaviors, alcohol use, and intergenerational violence are essential to delay or prevent IPV and safeguard women's wellbeing.
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    Preseason injury epidemiology and associated injury risk factors among South African junior provincial rugby players : a prospective cohort study
    Meyer, Kyle; Garnett, Daniel; Janse van Rensburg, Dina Christina; Fletcher, Lizelle; Viljoen, Carel Thomas (Taylor and Francis, 2026)
    BACKGROUND : The preseason period in rugby plays a key role in athlete preparation for the demands of the sport during the in-competition period. Epidemiological data pertaining to rugby have focused mainly on senior elite professional with little evidence available for junior elite professionals, and even less during the preseason period. This may limit the ability of stakeholders in the sport to understand the effects of injury on participants during the preseason period. OBJECTIVE : To determine the epidemiology, clinical characteristics, and associated risk factors for injury among elite male junior provincial rugby players in South Africa during a 14-week preseason period. DESIGN : A prospective cohort study. METHODS : Data collection procedures were in-line with consensus statements in sports and rugby. Prospective injury data related to 53 male participants were collected. Descriptive statistics was used to describe clinical characteristics of injury, cross-tabulations were created to investigate risk factor associations, and logistic regression was used to model the risk factors. RESULTS : The overall injury prevalence was 75.5%. The incidence of match play injuries (149.26/1000 h) were higher than training injuries (23.32/1000 h). Injuries to the lower limb (48.8%) and muscle/tendon injuries (48.2%) were most commonly reported injuries by anatomical region and tissue type during the preseason period. When controlling for age and playing position, baseline injury was associated with a higher risk of sustaining a subsequent injury during preseason. Age, baseline injury, and playing position showed no statistically significant association with injury risk. CONCLUSION : A high number of training and match play injury incidence were recorded for elite male junior provincial rugby players. Baseline injury was associated with a higher risk of sustaining a subsequent injury during preseason when controlling for playing position and age.
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    Preliminary evidence of extrarenal sodium storage in a large mammal : implications for comparative physiology and hypertension research : running : sodium storage in cattle
    Abraham, Andrew J.; Duvall, Ethan S.; Leese, Callum; Abraham, Kirstin; Le Roux, Elizabeth; Riond, Barbara; Ortmann, Sylvia; Terranova, Melissa; Leese, Graham; Bailey, Matthew A.; Clauss, Marcus (Springer, 2026-02)
    Under conditions of dietary sodium (Na+) excess, the kidneys may fail to adequately excrete Na+, potentially compromising blood pressure homeostasis. Body tissues, such as skin, can offer sites of short-term extrarenal Na+ storage and previous research has shown that this can help guard against hypertension in small mammals (e.g., rodents). Large mammals have relatively greater Na+ storage potential, but whether extrarenal Na+ storage occurs for this group is unknown. Here, we report preliminary evidence of extrarenal Na+ storage in cattle. We provided a large pulse-dose of NaCl to four cattle (body mass: ~720 kg) and measured excretion of Na+ and potassium (K+) in urine and faeces for a period of 7-days. Following NaCl administration, Na+ excretion spiked in both urine and faeces for ~ 48 h before returning to baseline measurements. After ~ 96 h, however, Na+ excretion increased again; a consistent physiological phenomenon across all individuals studied. We did not observe a pattern in urinary K+ excretion, indicating that the mechanism of Na+ storage does not appear to involve exchange for K+. However, faecal K+ excretion was reciprocal to that of Na+, presumably reflecting exchange of Na+/K+ across the walls of the large intestine. We infer that during the initial period of Na+ stress, short-term extrarenal Na+ storage occurred and the stored Na+ was later released only when the body had returned to Na+ homeostasis. Additional experiments are required to understand how patterns of Na+ regulation changes across body sizes and the specific body compartments involved. Cattle may be a useful model system for examining the impact of high Na+ intake in mammals larger than humans.