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dc.contributor.author | Schulman, M.L. (Martin)![]() |
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dc.contributor.author | Hayes, Nicole K.![]() |
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dc.contributor.author | Wilson, Tracy A.![]() |
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dc.contributor.author | Grewar, John Duncan![]() |
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dc.date.accessioned | 2024-12-09T11:22:08Z | |
dc.date.available | 2024-12-09T11:22:08Z | |
dc.date.issued | 2024-01-18 | |
dc.description.abstract | In North America, range constraints due to burgeoning development increasingly encroach on wild horse habitat and necessitate effective but humane reproductive management. The largest free-roaming wild horse fertility control program by population (>3500) and territory size (≈300,000 acres) is located within Nevada’s Virginia Range. Data from a field study investigated porcine zona pellucida (pZP) immunocontraception via remote dart delivery to mares in this population. Analyses aimed to measure efficacy by treatment effects on annual birth rates and population demographics and to evaluate treatment frequency and season against these variables. Analyses included mares’ monthly data (January 2019–December 2022; 48 months), characterized by cumulative vaccination numbers subset into four classifications considering the vaccine as having no loss of efficacy or a loss within a 6-, 12-, and 18-month period post vaccination; from foaling data, the likelihood of being in foal and of conceiving in that month; and from age, as mature or immature (<1 years-old). A downward foaling rate and trend in the numbers of mature mares, descriptively presented at monthly intervals, showed markedly declining annual seasonal breeding peaks, with no observed change in foaling season or duration. Within four years, population coverage surpassed 70% and was associated with a 58% reduction in foaling, with only a 10% conception rate. Vaccinated mares increased proportionally: assuming a 12-month decay rate, the system reached stability at an average ≈1.0 vaccination/mare/year, providing a robust recommendation for treatment frequency contributing to best management practices. | en_US |
dc.description.department | Veterinary Tropical Diseases | en_US |
dc.description.librarian | am2024 | en_US |
dc.description.sdg | SDG-15:Life on land | en_US |
dc.description.uri | https://www.mdpi.com/journal/vaccines | en_US |
dc.identifier.citation | Schulman, M.L.; Hayes, N.K.; Wilson, T.A.; Grewar, J.D. Immunocontraceptive Efficacy of Native Porcine Zona Pellucida (pZP) Treatment of Nevada’s Virginia Range Free-Roaming Horse Population. Vaccines 2024, 12, 96. https://DOI.org/10.3390/vaccines12010096. | en_US |
dc.identifier.issn | 2076-393X (online) | |
dc.identifier.other | 10.3390/vaccines12010096 | |
dc.identifier.uri | http://hdl.handle.net/2263/99804 | |
dc.language.iso | en | en_US |
dc.publisher | MDPI | en_US |
dc.rights | © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license. | en_US |
dc.subject | Porcine zona pellucida | en_US |
dc.subject | Vaccine | en_US |
dc.subject | Free-roaming horses | en_US |
dc.subject | Virginia range | en_US |
dc.subject | Porcine Zona pellucida (PZP) | en_US |
dc.subject | SDG-15: Life on land | en_US |
dc.title | Immunocontraceptive efficacy of native porcine Zona pellucida (pZP) treatment of Nevada’s Virginia range free-roaming horse population | en_US |
dc.type | Article | en_US |