Three separate acquisitions of bla NDM-1 in three different bacterial species from a single patient
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| dc.contributor.author | Mataseje, L.F.
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| dc.contributor.author | Pitout, Johann D.D.
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| dc.contributor.author | Croxen, M.
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| dc.contributor.author | Mulvey, M.R.
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| dc.contributor.author | Dingle, T.C.
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| dc.date.accessioned | 2024-06-07T12:45:43Z | |
| dc.date.available | 2024-06-07T12:45:43Z | |
| dc.date.issued | 2023-10 | |
| dc.description | DATA AVAILABILITY : Sequence data was uploaded to NCBI (BioProject PRJNA948358). | en_US |
| dc.description.abstract | To investigate the acquisition and relatedness of New Delhi Metallo-beta-lactamase among multiple separate species from one patient. Five isolates from three species (Pseudomonas aeruginosa; Pa, Acinetobacter baumannii; Ab and Proteus mirabilis; Pm) suspected of harbouring a carbapenemase were investigated by phenotype (antimicrobial susceptibilities) and whole genome sequencing. Epidemiological data was collected on this patient. Three different carbapenemase genes were detected; blaVIM-1 (Pa; ST773), blaOXA-23 (Ab, ST499) and blaNDM-1 identified in all isolates. NDM regions were found chromosomally integrated in all isolates. Data showed no evidence of NDM-1 transfer within this patient suggesting the enzyme was acquired in three separate events. | en_US |
| dc.description.department | Medical Microbiology | en_US |
| dc.description.librarian | am2024 | en_US |
| dc.description.sdg | SDG-03:Good heatlh and well-being | en_US |
| dc.description.sponsorship | The Public Health Agency of Canada. | en_US |
| dc.description.uri | http://link.springer.com/journal/10096 | en_US |
| dc.identifier.citation | Mataseje, L.F., Pitout, J., Croxen, M. et al. 2023, 'Three separate acquisitions of blaNDM‑1 in three different bacterial species from a single patient', European Journal of Clinical Microbiology & Infectious Diseases, vol. 42, pp. 1275-1280. https://DOI.org/10.1007/s10096-023-04651-4. | en_US |
| dc.identifier.issn | 0934-9723 (print) | |
| dc.identifier.issn | 1435-4373 (online) | |
| dc.identifier.other | 10.1007/s10096-023-04651-4 | |
| dc.identifier.uri | http://hdl.handle.net/2263/96345 | |
| dc.language.iso | en | en_US |
| dc.publisher | Springer | en_US |
| dc.rights | © The Author(s) 2023. This article is licensed under a Creative Commons Attribution 4.0 International License. | en_US |
| dc.subject | Carbapenemases | en_US |
| dc.subject | Canada | en_US |
| dc.subject | New Delhi metallo-beta-lactamase | en_US |
| dc.subject | Pseudomonas | en_US |
| dc.subject | Acientobacter | en_US |
| dc.subject | Proteus | en_US |
| dc.subject | SDG-03: Good health and well-being | en_US |
| dc.title | Three separate acquisitions of bla NDM-1 in three different bacterial species from a single patient | en_US |
| dc.type | Article | en_US |
