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| dc.contributor.author | Stark, Roderick T.
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| dc.contributor.author | Pye, Dominic R.
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| dc.contributor.author | Chen, Wenyi
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| dc.contributor.author | Newton, Oliver J.
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| dc.contributor.author | Deadman, Benjamin J.
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| dc.contributor.author | Miller, Philip W.
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| dc.contributor.author | Panayides, Jenny-Lee
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| dc.contributor.author | Riley, Darren Lyall
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| dc.contributor.author | Hellgardt, Klaus
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| dc.contributor.author | Hii, King Kuok (Mimi)
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| dc.date.accessioned | 2023-10-16T07:37:26Z | |
| dc.date.available | 2023-10-16T07:37:26Z | |
| dc.date.issued | 2022-10 | |
| dc.description.abstract | A synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a sustainable manufacturing process in South Africa. Quantitative metrics were employed to evaluate the sustainability of the key steps of the reaction. | en_US |
| dc.description.department | Chemistry | en_US |
| dc.description.librarian | am2023 | en_US |
| dc.description.sponsorship | The ROAR facility by EPSRC. | en_US |
| dc.description.uri | https://pubs.rsc.org/en/journals/journalissues/re | en_US |
| dc.identifier.citation | Stark, R.T., Pye, D.R., Chen, W. et al. 2022, 'Assessing a sustainable manufacturing route to lapatinib', Reaction Chemistry and Engineering, vol. 7, no. 11, pp. 2420-2426, doi : 10.1039/d2re00267a. | en_US |
| dc.identifier.issn | 2058-9883 (online) | |
| dc.identifier.other | 10.1039/d2re00267a | |
| dc.identifier.uri | http://hdl.handle.net/2263/92873 | |
| dc.language.iso | en | en_US |
| dc.publisher | Royal Society of Chemistry | en_US |
| dc.rights | © The Royal Society of Chemistry 2022. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. | en_US |
| dc.subject | Anti-cancer drug | en_US |
| dc.subject | Lapatinib | en_US |
| dc.subject | Quantitative metrics | en_US |
| dc.subject | SDG-03: Good health and well-being | en_US |
| dc.subject | South Africa (SA) | en_US |
| dc.title | Assessing a sustainable manufacturing route to lapatinib | en_US |
| dc.type | Article | en_US |
