dc.contributor.author |
Mambwe, Dickson
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|
dc.contributor.author |
Korkor, Constance M.
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|
dc.contributor.author |
Mabhula, Amanda
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|
dc.contributor.author |
Ngqumba, Zama
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|
dc.contributor.author |
Cloete, Cleavon
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|
dc.contributor.author |
Kumar, Malkeet
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|
dc.contributor.author |
Barros, Paula Ladeia
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|
dc.contributor.author |
Leshabane, Meta Kgaogelo
|
|
dc.contributor.author |
Coertzen, Dina
|
|
dc.contributor.author |
Taylor, Dale
|
|
dc.contributor.author |
Gibhard, Liezl
|
|
dc.contributor.author |
Njoroge, Mathew
|
|
dc.contributor.author |
Lawrence, Nina
|
|
dc.contributor.author |
Reader, Janette
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|
dc.contributor.author |
Moreira, Diogo Rodrigo
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|
dc.contributor.author |
Birkholtz, Lyn-Marie
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|
dc.contributor.author |
Wittlin, Sergio
|
|
dc.contributor.author |
Egan, Timothy J.
|
|
dc.contributor.author |
Chibale, Kelly
|
|
dc.date.accessioned |
2023-02-24T08:08:34Z |
|
dc.date.issued |
2022-12 |
|
dc.description.abstract |
Please read abstract in the article. |
en_US |
dc.description.department |
Biochemistry |
en_US |
dc.description.department |
Genetics |
en_US |
dc.description.department |
Microbiology and Plant Pathology |
en_US |
dc.description.department |
UP Centre for Sustainable Malaria Control (UP CSMC) |
en_US |
dc.description.embargo |
2023-12-12 |
|
dc.description.librarian |
hj2023 |
en_US |
dc.description.uri |
http://pubs.acs.org/loi/jmcmar |
en_US |
dc.identifier.citation |
Mambwe, D., Korkor, C.M., Mabhula, A. et al. 2022, 'Novel 3-trifluoromethyl-1,2,4-oxadiazole analogues of astemizole with multi-stage antiplasmodium activity and in vivo efficacy in a Plasmodium berghei mouse malaria infection model', Journal of Medicinal Chemistry, vol. 65, no. 24, pp. 16695–16715, doi : 10.1021/acs.jmedchem.2c01516. |
en_US |
dc.identifier.issn |
0022-2623 (print) |
|
dc.identifier.issn |
1520-4804 (online) |
|
dc.identifier.other |
10.1021/acs.jmedchem.2c01516 |
|
dc.identifier.uri |
https://repository.up.ac.za/handle/2263/89809 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
American Chemical Society |
en_US |
dc.rights |
This document is the Accepted Manuscript version of a Published Work that appeared in final form in Journal of Medicinal Chemistry, © 2022 American Chemical Society after peer review and technical editing by the publisher. [12 months embargo] |
en_US |
dc.subject |
Astemizole |
en_US |
dc.subject |
Repositioning |
en_US |
dc.subject |
Plasmodium falciparum |
en_US |
dc.subject |
Plasmodium berghei |
en_US |
dc.subject |
Human ether-á-go-go-related gene (hERG) |
en_US |
dc.subject |
Live-cell microscopy |
en_US |
dc.title |
Novel 3-trifluoromethyl-1,2,4-oxadiazole analogues of astemizole with multi-stage antiplasmodium activity and in vivo efficacy in a Plasmodium berghei mouse malaria infection model |
en_US |
dc.type |
Postprint Article |
en_US |