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Biochemistry, Genetics and Microbiology (BGM): Recent submissions

  • In vitro evaluation of the application of an optimized xylanase cocktail for improved monogastric feed digestibility 
    Ramatsui, Lebogang; Sithole, Tariro; Gandla, Madhavi L.; Jönsson, Leif J.; Edkins, Adrienne L.; Malgas, Samkelo; Pletschke, Brett I. (Wiley, 2024-05)
    Xylanases from glycoside hydrolase (GH) families 10 and 11 are common feed additives for broiler chicken diets due to their catalytic activity on the nonstarch polysaccharide xylan. This study investigated the potential ...
  • Clonality and limited population diversity of Fusarium circinatum in Colombia 
    Ceriani, Callin; Wingfield, Michael J.; Fru, Felix Fon; Van Wyk, S.; Rodas, Carlos A.; Wingfield, Brenda D.; Steenkamp, Emma Theodora (Wiley, 2024-06)
    Fusarium circinatum is an important fungal pathogen of Pinus species utilized in commercial forestry worldwide. In Colombia, it was first found on nursery plants and later in plantations associated with basal cankers on ...
  • Biology and pathogenicity of fungi causing husk rot of macadamia in South Africa 
    Twiddy, Dee Ingrid; Fouché, Arista; Akinsanmi, Olufemi A.; Fourie, Gerda (Springer, 2024-07)
    Fungal diseases of macadamia fruit in South Africa have the potential to cause notable economic damage in this rapidly growing industry. To improve our understanding of the species involved in husk rot in macadamia orchards, ...
  • Exploring the modulatory influence on the antimalarial activity of amodiaquine using scaffold hybridisation with ferrocene integration 
    Mbaba, Mziyanda; Golding, Taryn M.; Omondi, Reinner O.; Mohunlal, Roxanne; Egan, Timothy J.; Reader, Janette; Birkholtz, Lyn-Marie; Smith, Gregory S. (Elsevier, 2024-05)
    Amodiaquine (AQ) is a potent antimalarial drug used in combination with artesunate as part of artemisinin-based combination therapies (ACTs) for malarial treatment. Due to the rising emergence of resistant malaria parasites, ...
  • Chromosome 20p11.2 deletions cause congenital hyperinsulinism via the loss of FOXA2 or its regulatory elements 
    Laver, Thomas W.; Wakeling, Matthew N.; Caswell, Richard C.; Bunce, Benjamin; Yau, Daphne; Mannisto, Jonna M.E.; Houghton, Jayne A.L.; Hopkins, Jasmin J.; Weedon, Michael N.; Saraff, Vrinda; Kershaw, Melanie; Honey, Engela M.; Murphy, Nuala; Giri, Dinesh; Nath, Stuart; Saredo, Ana Tangari; Banerjee, Indraneel; Hussain, Khalid; Owens, Nick D.L. (Nature Research, 2024-07)
    Persistent congenital hyperinsulinism (HI) is a rare genetically heterogeneous condition characterised by dysregulated insulin secretion leading to life-threatening hypoglycaemia. For up to 50% of affected individuals ...
  • Maize–Fusarium associations and their mycotoxins : insights from South Africa 
    Visagie, Cobus M.; Meyer, Hannalien; Yilmaz, Neriman (Elsevier, 2024)
    For maize, a staple food in South Africa, there is a lack of comprehensive knowledge on the mycotoxin-producing fungal diversity. In this study, a fungal community profile was established using culture-dependent methods ...
  • Antagonistic potential of endophytic fungal isolates of tomato (Solanum lycopersicum L.) fruits against post-harvest disease-causing pathogens of tomatoes : an in vitro investigation 
    Ramudingana, Phathutshedzo; Mamphogoro, Tshifhiwa Paris; Kamutando, Casper Nyaradzai; Maboko, Martin Makgose; Modika, Kedibone Yvonne; Moloto, Kgantjie Walter; Thantsha, Mapitsi Silvester (Elsevier, 2024-06)
    Post-harvest decay of fresh agricultural produce is a major threat to food security globally. Synthetic fungicides, commonly used in practice for managing the post-harvest losses, have negative impacts on consumers’ health. ...
  • UNITY : a low-field magnetic resonance neuroimaging initiative to characterize neurodevelopment in low and middle-income settings 
    Abate, F.; Adu-Amankwah, A.; Ae-Ngibise, K.A.; Agbokey, F.; Agyemang, V.A.; Agyemang, C.T.; Akgun, C.; Ametepe, J.; Arichi, T.; Asante, K.P.; Balaji, S.; Baljer, L.; Basser, P.J.; Beauchemin, J.; Bennallick, C.; Berhane, Y.; Boateng-Mensah, Y.; Bourke, N.J.; Bradford, L.; Bruchhage, M.M.K.; Cano Lorente, R.; Cawley, P.; Cercignani, M.; D Sa, V.; De Canha, A.; Navarro, N.D.; Dean, D.C., III; Delarosa, J.; Donald, K.A.; Dvorak, A.; Edwards, A.D.; Field, D.; Frail, H.; Freeman, B.; George, T.; Gholam, J.; Guerrero-Gonzalez, J.; Hajnal, J.V.; Haque, R.; Hollander, W.; Hoodbhoy, Z.; Huentelman, M.; Jafri, S.K.; Jones, D.K.; Joubert, Fourie; Karaulanov, T.; Kasaro, M.P.; Knackstedt, S.; Kolind, S.; Koshy, B.; Kravitz, R.; Lafayette, S.L.; Lee, A.C.; Lena, B.; Lepore, N.; Linguraru, M.; Ljungberg, E.; Lockhat, Zarina I.; Loth, E.; Mannam, P.; Masemola, K.M.; Moran, R.; Murphy, D.; Nakwa, F.L.; Nankabirwa, V.; Nelson, C.A.; North, K.; Nyame, S.; O Halloran, R.; O'Muircheartaigh, J.; Oakley, B.F.; Odendaal, H.; Ongeti, C.M.; Onyango, D.; Oppong, S.A.; Padormo, F.; Parvez, D.; Paus, T.; Pepper, Michael Sean; Phiri, K.S.; Poorman, M.; Ringshaw, J.E.; Rogers, J.; Rutherford, M.; Sabir, H.; Sacolick, L.; Seal, M.; Sekoli, M.L.; Shama, T.; Siddiqui, K.; Sindano, N.; Spelke, M.B.; Springer, P.E.; Suleman, Farhana Ebrahim; Sundgren, P.C.; Teixeira, R.; Terekegn, W.; Traughber, M.; Tuuli, M.G.; Van Rensburg, Jeanne; Váša, F.; Velaphi, S.; Velasco, P.; Viljoen, I.M.; Vokhiwa, M.; Webb, A.; Weiant, C.; Wiley, N.; Wintermark, P.; Yibetal, K.; Deoni, S.C.L.; Williams, S.C.R. (Elsevier, 2024-10)
    Measures of physical growth, such as weight and height have long been the predominant outcomes for monitoring child health and evaluating interventional outcomes in public health studies, including those that may impact ...
  • Dosage sensitivity shapes balanced expression and gene longevity of homoeologs after whole-genome duplications in angiosperms 
    Shi, Tao; Gao, Zhiyan; Chen, Jinming; Van de Peer, Yves (Oxford University Press, 2024-10)
    Please read abstract in the article.
  • Botryosphaeriaceae species associated with branch dieback and decline of macadamia trees in South Africa 
    Maduke, Angel N.; Slippers, Bernard; Van der Linde, Elna; Wingfield, Michael J.; Fourie, Gerda (Springer, 2024)
    Botryosphaeriaceae species are important latent pathogens causing diseases on trees utilized in forestry and agriculture. In recent years, there has been an increase in the incidence and severity of branch dieback and ...
  • Interspecific transfer of genetic information through polyploid bridges 
    Kauai, Felipe; Bafort, Quinten; Mortier, Frederik; Van Montagu, Marc; Bonte, Dries; Van de Peer, Yves (National Academy of Sciences, 2024-05)
    Hybridization blurs species boundaries and leads to intertwined lineages resulting in reticulate evolution. Polyploidy, the outcome of whole genome duplication (WGD), has more recently been implicated in promoting and ...
  • The duplication of genomes and genetic networks and its potential for evolutionary adaptation and survival during environmental turmoil 
    Ebadi, Mehrshad; Bafort, Quinten; Mizrachi, Eshchar; Audenaert, Pieter; Simoens, Pieter; Van Montagu, Marc; Bonte, Dries; Van de Peer, Yves (National Academy of Sciences, 2023-10-03)
    The importance of whole-genome duplication (WGD) for evolution is controversial. Whereas some view WGD mainly as detrimental and an evolutionary dead end, there is growing evidence that polyploidization can help overcome ...
  • Standing genetic variation fuels rapid evolution of herbicide resistance in blackgrass 
    Kersten, Sonja; Chang, Jiyang; Huber, Christian D.; Voichek, Yoav; Lanz, Christa; Hagmaier, Timo; Lang, Patricia; Lutz, Ulrich; Hirschberg, Insa; Lerchl, Jens; Porri, Aimone; Van de Peer, Yves; Schmid, Karl; Weigel, Detlef; Rabanal, Fernando A. (National Academy of Sciences, 2023-04)
    Repeated herbicide applications in agricultural fields exert strong selection on weeds such as blackgrass (Alopecurus myosuroides), which is a major threat for temperate climate cereal crops. This inadvertent selection ...
  • Bacterial and genetic features of raw retail pork meat : integrative analysis of antibiotic susceptibility, whole-genome sequencing, and metagenomics 
    Lowe, Michelle; Strasheim, Wilhelmina; Chan, Wai Yin; Perovic, Olga (MDPI, 2024-08)
    The global antibiotic resistance crisis, driven by overuse and misuse of antibiotics, is multifaceted. This study aimed to assess the microbiological and genetic characteristics of raw retail pork meat through various ...
  • Isolation and characterization of potential lignin peroxidase-producing bacteria from compost samples at Richards Bay (South Africa) 
    Dube, Sindiswa L.; Osunsanmi, Foluso O.; Ngcobo, Bongekile P.; Mkhwanazi, Londiwe B.; Jobe, Zanele Z.; Aruleba, Raphael T.; Mosa, Rebamang Anthony; Opoku, Andrew R. (Sciendo, 2023-06)
    Lignin recalcitrance is a key issue in producing value-added products from lignocellulose biomass. In situ biodegradable lignin-modifying enzymes-producing bacteria are considered a suitable solution to lignin biodegradation ...
  • Temporal dynamics of microbial transcription in wetted hyperarid desert soils 
    Leon-Sobrino, Carlos; Ramond, Jean-Baptiste; Coclet, Clement; Kapitango, Ritha-Meriam; Maggs‑Kolling, Gillian; Cowan, Don A. (Oxford University Press, 2024-03)
    Rainfall is rare in hyperarid deserts but, when it occurs, it triggers large biological responses essential for the long-term maintenance of the ecosystem. In drylands, microbes play major roles in nutrient cycling, but ...
  • Changes in nutrient availability substantially alter bacteria and extracellular enzymatic activities in Antarctic soils 
    Nair, Girish R.; Kooverjee, Bhaveni B.; De Scally, Storme Z.; Cowan, Don A.; Makhalanyane, Thulani Peter (Oxford University Press, 2024-06)
    In polar regions, global warming has accelerated the melting of glacial and buried ice, resulting in meltwater run-off and the mobilization of surface nutrients. Yet, the short-term effects of altered nutrient regimes on ...
  • Symbiotic nitrogen fixation efficiency of native rhizobia in selected South African legume crops 
    Ndhlovu, Khumbudzo (University of Pretoria, 2019-06)
    This Master’s dissertation reports about the screening and characterization of selected alpha and beta rhizobial isolates from wild legumes in South Africa for their nodulation and nitrogen fixation properties on the ...
  • Characterisation of secondary metabolite pathways in the Ceratocystidaceae 
    Sayari, Mohammad (University of Pretoria, 2019-12)
    Members of Ceratocystistidaceae (phylum Ascomycota, class Sordariomycetes) include fungal pathogens that cause diseases on a broad spectrum of hosts, leading to substantial economic losses globally. The objective of this ...
  • Structural and biophysical characterization of the secreted, β-helical adhesin EtpA of Enterotoxigenic Escherichia coli 
    Ntui, Clifford Manyo; Fleckenstein, James M.; Schubert, Wolf-Dieter (Public Library of Science, 2023-07)
    Enterotoxigenic Escherichia coli (ETEC) is a diarrhoeal pathogen associated with high morbidity and mortality especially among young children in developing countries. At present, there is no vaccine for ETEC. One candidate ...