Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis
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| dc.contributor.advisor | Pepper, Michael Sean | |
| dc.contributor.coadvisor | Durandt, Chrisna | |
| dc.contributor.coadvisor | Ambele, Melvin | |
| dc.contributor.postgraduate | Giles, Rachel | |
| dc.date.accessioned | 2022-07-25T10:44:43Z | |
| dc.date.available | 2022-07-25T10:44:43Z | |
| dc.date.created | 2022 | |
| dc.date.issued | 2022 | |
| dc.description | Dissertation (MSc (Medical Immunology))--University of Pretoria, 2022. | en_US |
| dc.description.abstract | The aim of this project was to develop assays that will allow for high-throughput screening to monitor adipogenesis. Such an assay may be useful for the identification of potential drug targets during the process of adipogenesis, which may result in discovering novel solutions to combat obesity and its related comorbidities. The main question for this study is whether adipogenesis can be assessed in smaller well sizes (such as the 96-well plate) with confidence using the specified methods. | en_US |
| dc.description.availability | Unrestricted | en_US |
| dc.description.degree | MSc (Medical Immunology) | en_US |
| dc.description.department | Immunology | en_US |
| dc.description.sponsorship | NRF Masters Scholarship 2020 | en_US |
| dc.identifier.citation | * | en_US |
| dc.identifier.doi | https://doi.org/10.25403/UPresearchdata.20348028 | en_US |
| dc.identifier.other | S2022 | |
| dc.identifier.uri | https://repository.up.ac.za/handle/2263/86431 | |
| dc.identifier.uri | DOI: 10.25403/UPresearchdata.20348028 | |
| dc.language.iso | en | en_US |
| dc.publisher | University of Pretoria | |
| dc.rights | © 2022 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria. | |
| dc.subject | Immunology | en_US |
| dc.subject | Assays | en_US |
| dc.subject | Adipogenesis | en_US |
| dc.subject | Drug targeting | en_US |
| dc.subject | 96 well plate | en_US |
| dc.subject | UCTD | |
| dc.title | Development of a high-throughput screening assay to evaluate compound libraries for the modulation of adipogenesis | en_US |
| dc.type | Dissertation | en_US |
