dc.contributor.author |
Botha, C.J. (Christoffel Jacobus)
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dc.contributor.author |
Venter, Elna
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dc.contributor.other |
University of Pretoria. Faculty of Veterinary Science. Dept. of Paraclinical Sciences. Section Pharmacology and Toxicology |
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dc.coverage.spatial |
Africa |
en |
dc.coverage.spatial |
South Africa |
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dc.date |
DISTRIBUTION:
Annual weeds, widespread, to be found on disturbed soils. Botanical description: There are about 150 species of Amaranthus to be found in South Africa, of which 9 are weeds. Only A. thunbergii is indigenous. Usually they all turn red when fully grown.
Toxic principle: Nitrate / Nitrite. |
en |
dc.date.accessioned |
2008-12-22T08:45:58Z |
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dc.date.available |
2008-12-22T08:45:58Z |
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dc.date.issued |
2002 |
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dc.description |
Colour photos. Final web-ready size: JPEG. Photo 1: 31.8 kb, 96 ppi; Photo 2: 35.6 kb, 72 ppi; Photo 3: 21.3 kb, 72 ppi; Photo 4: 9.2 kb, 72 ppi. Original TIFF file housed at the Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology, University of Pretoria. |
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dc.description.abstract |
MECHANISM OF ACTION:
In the rumen nitrate is reduced to nitrite and following absorption haemoglobin is oxidised to methaemoglobin. |
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dc.description.abstract |
TOXICITY:
• Great variations both inter- and intraspecies
• Nitrate - c. 0,5 g/kg sheep - 5g/kg cattle
• Nitrite - c. 20 mg/kg sheep - 100mg/kg cattle
For soluble oxalate poisoning, go to Urogenital Menu. |
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dc.description.abstract |
SYNDROMES:
Nitrate/nitrite poisoning. |
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dc.description.abstract |
SYSTEMS AFFECTED:
Haemopoietic system. |
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dc.description.abstract |
CLINICAL SIGNS:
Acute poisoning:
Respiratory System:
• Hyperpnoea
• Dyspnoea
• Anoxia precipitated by exercise
Central Nervous System:
• Ataxia
• Tremors
• Weakness
• Terminal convulsions (brain anoxia)
Cardiovascular System:
• Cardiovascular failure, syncope
• Cyanosis
• Methaemoglobinaemia: Blood & mucous membranes a dirty chocolate brown colour
• Rapid weak pulse (drop in blood pressure)
Gastrointestinal Tract:
• Diarrhoea
• Salivation (vomition)
Abortion - especially last trimester
For soluble oxalate poisoning, go the Urogenital Menu. |
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dc.description.abstract |
NECROPSY:
Macroscopical findings:
• Cyanosis• Tarry, dark, red-brown to brown blood• Tissues and mucous membranes brown (Not apparent in every case)
• Congestion
• Petechial and ecchymotic haemorrhages on mucosal, visceral and serosal surfaces. |
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dc.description.abstract |
HISTOPATHOLOGY:
• Nothing unusual or pathognomonic
For soluble oxalate poisoning, go the Urogenital Menu. |
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dc.description.abstract |
TREATMENT:
1. Methylene blue. Acts as intermediate electron acceptor that accelerates the reaction between NADPH and methaemoglobin.
2. Ascorbic acid. Also used in dogs for paracetamol poisoning. |
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dc.description.uri |
http://www.library.up.ac.za/vet/poison |
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dc.identifier.citation |
Botha, CJ & Venter, E 2002, 'Plants poisonous to livestock Southern Africa (CD-ROM)' University of Pretoria, Faculty of Veterinary Science, Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology, Pretoria, South Africa. |
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dc.identifier.uri |
http://hdl.handle.net/2263/8517 |
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dc.rights |
©University of Pretoria. Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology (Original and digital). Provided for educational purposes only. It may not be downloaded, reproduced or distributed in any format without written permission of the original copyright holder. Any attempt to circumvent the access controls placed on this file is a violation of copyright laws and is subject to criminal prosecution. Please contact the collection administrator for copyright issues. |
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dc.source |
Original format: University of Pretoria, Faculty of Veterinary Science. |
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dc.subject |
Plant poisoning |
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dc.subject |
Toxicology |
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dc.subject |
Plant poisoning in animals |
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dc.subject |
Poisonous plants |
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dc.subject |
Nitrate |
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dc.subject |
Nitrite |
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dc.subject |
Methaemoglobin |
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dc.subject.lcsh |
Poisonous plants -- Toxicology -- Africa, Southern |
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dc.subject.lcsh |
Veterinary toxicology |
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dc.title |
Amaranthus species |
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dc.title.alternative |
Pigweed |
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dc.title.alternative |
Hanekam |
af |
dc.title.alternative |
Cockscomb |
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dc.title.alternative |
Misbredie |
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dc.type |
Still Image |
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