Fusarium verticillioides

Botha, C.J. (Christoffel Jacobus); Venter, Elna

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dc.contributor.author	Botha, C.J. (Christoffel Jacobus)
dc.contributor.author	Venter, Elna
dc.contributor.other	University of Pretoria. Faculty of Veterinary Science. Dept. of Paraclinical Sciences. Section Pharmacology and Toxicology
dc.coverage.spatial	Africa	en
dc.coverage.spatial	South Africa	en
dc.date.accessioned	2008-12-18T09:58:00Z
dc.date.available	2008-12-18T09:58:00Z
dc.date.issued	2002
dc.description	Colour photos. Final web-ready size: JPEG, 72 ppi. Photo 1: 45.9 kb; Photo 2: 12.5 kb; Photo 3: 10.8 kb. Original TIFF file housed at the Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology, University of Pretoria.	en
dc.description.abstract	DISTRIBUTION: A fungus that is one of the most prevalent moulds on harvested maize throughout the world. Maize is produced mainly in the North-West, the north-western, northern and eastern Free State, the Mpumalanga Highveld and the KwaZulu-Natal Midlands.	en
dc.description.abstract	BOTANICAL DESCRIPTION: General: A cosmopolitan fungus and one of the most common moulds on harvested maize worldwide. A cause of cob rot (kopvrot).	en
dc.description.abstract	TOXIC PRINCIPLE: • Fumonisin B1. • Several other toxic metabolites were isolated, but not of significance for LEM. • Fumonisin B1 is structurally similar to sphingosine, which is the backbone of sphingolipids. • Fumonisin inhibits sphingolipid synthesis.	en
dc.description.abstract	SYNDROMES: Leukoencephalomalacia (LEM).	en
dc.description.abstract	SYSTEMS AFFECTED: Central nervous and respiratory systems.	en
dc.description.abstract	CLINICAL SIGNS: • Leukoencephalomalacia (LEM) is a mycotoxicosis of horses following ingestion of maize contaminated by Fusarium verticillioides. • The disease is characterized by focal liquefactive necrosis of the cerebral white matter. • Horses exhibit a variety of nervous signs depending on where the lesions are in the cerebrum. • The intoxication is invariably fatal. • Lung oedema is seen in pigs.	en
dc.description.abstract	NECROPSY: Subcortical focal areas of liquefactive necrosis and haemorrhage.	en
dc.description.uri	http://www.library.up.ac.za/vet/poison	en
dc.identifier.citation	Botha, CJ & Venter, E 2002, 'Plants poisonous to livestock Southern Africa (CD-ROM)' University of Pretoria, Faculty of Veterinary Science, Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology, Pretoria, South Africa.	en
dc.identifier.uri	http://hdl.handle.net/2263/8460
dc.rights	©University of Pretoria. Dept. of Paraclinical Sciences, Section Pharmacology and Toxicology (Original and digital). Provided for educational purposes only. It may not be downloaded, reproduced or distributed in any format without written permission of the original copyright holder. Any attempt to circumvent the access controls placed on this file is a violation of copyright laws and is subject to criminal prosecution. Please contact the collection administrator for copyright issues.	en
dc.source	Original format: University of Pretoria, Faculty of Veterinary Science.	en
dc.subject	Plant poisoning	en
dc.subject	Toxicology	en
dc.subject	Plant poisoning in animals	en
dc.subject	Poisonous plants	en
dc.subject	LEM	en
dc.subject	Leukoencephalomalacia	en
dc.subject	Fumonisins	en
dc.subject.lcsh	Poisonous plants -- Toxicology -- Africa, Southern	en
dc.subject.lcsh	Veterinary toxicology	en
dc.title	Fusarium verticillioides	en
dc.title.alternative	Fusarium moniliforme	en
dc.title.alternative	Maize fungus	en
dc.title.alternative	Mieliefungus	af
dc.title.alternative	Cob rot	en
dc.title.alternative	Kopvrot	af
dc.type	Still Image	en