Evaluating the pharmacoeconomic impact of nutrient supplementation post-operatively on patients receiving Roux-Y gastric bypass vs. biliopancreatic diversion with duodenal switch

We are excited to announce that the repository will soon undergo an upgrade, featuring a new look and feel along with several enhanced features to improve your experience. Please be on the lookout for further updates and announcements regarding the launch date. We appreciate your support and look forward to unveiling the improved platform soon.

Show simple item record

dc.contributor.author Van Vollenstee, Fiona A.
dc.contributor.author Van der Merwe, Maria-Teresa
dc.date.accessioned 2022-02-10T05:18:20Z
dc.date.available 2022-02-10T05:18:20Z
dc.date.issued 2021-06
dc.description.abstract BACKGROUND : Without the needed medical support, bariatric surgery can be associated with post-operative malnutrition and associated nutrient deficiencies. We aimed to evaluate the cost difference of perioperative infusion requirements and TPN between GBP and BPD-DS. METHODS : All patients undergoing GBP or BPD-DS procedures between August 2015 and June 2018 were included. Information was collected to standardize the nutritional information into two categories: (1) oral supplementation and standard intravenous infusions, as predicted costs forming part of preoperative quote and (2) infusions prescribed for malnutrition, based on blood biochemistry, caterized as unexpected costs. RESULTS : A total of 573 patients over 3 years (GBP 60%, BPD-DS 40%) were included in the analysis. The average predicted costs from oral supplementation for both surgery groups and prophylactic infusions for BPD-DS were GBP (46.90USD) vs. BPD-DS (154.13 USD) (p-value = NS). Unexpected costs for infusions to correct nutritional deficiencies were GBP (199.14 USD) vs. BPD-DS (127.29 USD) (p-value = NS). TPN incidence rate was GBP (2.1%) and BPD-DS (12.7%) (p-value < 0.001) and admission rate per patient was GBP (0.9) and BPD-DS (0.63) (p-value < 0.05). Costs for acquiring TPN were GBP (153.58 USD) vs. BPD-DS (268.76 USD). Total unexpected costs were GBP (352.72 USD) vs. BPD-DS (396.05 USD) (p-value = NS). CONCLUSION : Nutrient deficiencies are known to occur within both GBP and BPD-DS surgeries, even up to 3 years. The admission rate/patient, requiring TPN, was higher in the GBP group, indicating that BPD-DS surgery can be efficient and cost-effective with holistic and multitherapeutic post-surgery care. BPD-DS procedures should be reserved for centers with a comprehensive and experienced multidisciplinary team enforcing stringent follow-up regimes. en_ZA
dc.description.department Internal Medicine en_ZA
dc.description.librarian hj2022 en_ZA
dc.description.uri https://www.springer.com/journal/11695 en_ZA
dc.identifier.citation Van Vollenstee, F.A., Van der Merwe, M.T. Evaluating the Pharmacoeconomic Impact of Nutrient Supplementation Post-operatively on Patients Receiving Roux-Y Gastric Bypass vs. Biliopancreatic Diversion with Duodenal Switch. Obesity Surgery 31, 2434–2443 (2021). https://doi.org/10.1007/s11695-021-05268-2. en_ZA
dc.identifier.issn 0960-8923 (print)
dc.identifier.issn 1708-0428 (online)
dc.identifier.other 10.1007/s11695-021-05268-2
dc.identifier.uri http://hdl.handle.net/2263/83744
dc.language.iso en en_ZA
dc.publisher Springer en_ZA
dc.rights © The Author(s) 2021. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License. en_ZA
dc.subject Bariatric surgery en_ZA
dc.subject Pharmacoeconomics en_ZA
dc.subject Costs en_ZA
dc.subject Supplementation en_ZA
dc.subject Nutrient deficiencies en_ZA
dc.subject Total parenteral nutrition (TPN) en_ZA
dc.title Evaluating the pharmacoeconomic impact of nutrient supplementation post-operatively on patients receiving Roux-Y gastric bypass vs. biliopancreatic diversion with duodenal switch en_ZA
dc.type Article en_ZA


Files in this item

This item appears in the following Collection(s)

Show simple item record