Analysis of maternal serum vitamin D concentrations at birth in women presenting with spontaneous preterm birth : a case-control study

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dc.contributor.author Chiudzu, Grace
dc.contributor.author Maluwa, Alfred
dc.contributor.author Choko, Augustine
dc.contributor.author Odland, Jon Oyvind
dc.date.accessioned 2022-01-28T09:56:25Z
dc.date.available 2022-01-28T09:56:25Z
dc.date.issued 2021-04
dc.description.abstract Vitamin D is a potent immune system modulator; its deficiency correlates with increased susceptibility to infections. We evaluated the status of maternal serum vitamin D in women with spontaneous preterm birth. In this case-control study, the maternal serum concentration of vitamin D (25OH D) was measured in 95 women delivering preterm and 92 women having a term birth. Vitamin D sufficiency was found in 79% of the mothers who delivered preterm and 80.4% of the mothers who had term birth (p=0.822). There was a negative correlation between maternal serum concentration of 25 Hydroxyvitamin D and maternal age in the preterm birth group (p=0.043). In conclusion, there was no difference in maternal serum concentrations of 25 Hydroxyvitamin D between women delivering preterm compared to those having term birth. Maternal serum concentration of 25 Hydroxyvitamin D is not associated with occurrence of preterm birth. en_ZA
dc.description.abstract La vitamine D est un puissant modulateur du système immunitaire; sa carence est corrélée à une sensibilité accrue aux infections. Nous avons évalué le statut de la vitamine D sérique maternelle chez les femmes ayant une naissance prématurée spontanée. Dans cette étude cas-témoins, la concentration sérique maternelle de vitamine D (25OH D) a été mesurée chez 95 femmes ayant accouché avant terme et 92 femmes ayant une naissance à terme. Une suffisance en vitamine D a été trouvée chez 79% des mères qui ont accouché prématurément et 80,4% des mères qui ont eu un accouchement à terme (p = 0,822). Il y avait une corrélation négative entre la concentration sérique maternelle de 25 hydroxyvitamine D et l'âge maternel dans le groupe des naissances prématurées (p = 0,043). En conclusion, il n'y avait aucune différence dans les concentrations sériques maternelles de 25 Hydroxyvitamine D entre les femmes ayant accouché avant terme et celles ayant une naissance à terme. La concentration sérique maternelle de 25 hydroxyvitamine D n'est pas associée à la survenue d'un accouchement prématuré. en_ZA
dc.description.department School of Health Systems and Public Health (SHSPH) en_ZA
dc.description.librarian am2022 en_ZA
dc.description.uri https://journals.co.za/journal/ajrh en_ZA
dc.identifier.citation Chiudzu, G., Maluwa, A., Choko, A. et al. 2021, 'Analysis of maternal serum vitamin D concentrations at birth in women presenting with spontaneous preterm birth : a case-control study', African Journal of Reproductive Health, vol. 25, no. 2, pp. 103-109. en_ZA
dc.identifier.issn 1118-4841
dc.identifier.other 10.29063/ajrh2021/v25i2.10
dc.identifier.uri http://hdl.handle.net/2263/83510
dc.language.iso en en_ZA
dc.publisher Women's Health and Action Research Centre (WHARC) en_ZA
dc.rights Women's Health and Action Research Centre (WHARC) en_ZA
dc.subject Preterm birth en_ZA
dc.subject Vitamin D en_ZA
dc.subject Preterm delivery en_ZA
dc.subject 25 Hydroxyvitamin D en_ZA
dc.subject Premature en_ZA
dc.subject Naissance prematuree en_ZA
dc.subject Vitamine D en_ZA
dc.subject Accouchement premature en_ZA
dc.subject 25 hydroxyvitamine D en_ZA
dc.subject Prematuree en_ZA
dc.title Analysis of maternal serum vitamin D concentrations at birth in women presenting with spontaneous preterm birth : a case-control study en_ZA
dc.type Article en_ZA


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