Abstract:
Tsetse transmitted trypanosomiasis is a fatal disease commonly known as Nagana in cattle
and sleeping sickness in humans. The disease threatens food security and has severe economic
impact in Africa including most parts of Zambia. The level of e ectiveness of commonly used African
trypanosomiasis control methods has been reported in several studies. However, there have been no
review studies on African trypanosomiasis control and management conducted in the context of One
Health. This paper therefore seeks to fill this knowledge gap. A review of studies that have been
conducted on African trypanosomiasis in Zambia between 2009 and 2019, with a focus on the control
and management of trypanosomiasis was conducted. A total of 2238 articles were screened, with
application of the search engines PubMed, PubMed Central and One Search. Out of these articles,
18 matched the required criteria and constituted the basis for the paper. An in-depth analysis of
the 18 articles was conducted to identify knowledge gaps and evidence for best practices. Findings
from this review provide stakeholders and health workers with a basis for prioritisation of African
trypanosomiasis as an important neglected disease in Zambia and for formulation of One Health
strategies for better control and/or management of the disease.
