A bioeconomic model for the optimization of local canine rabies control

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dc.contributor.author Anderson, Aaron
dc.contributor.author Kotze, Johann
dc.contributor.author Shwiff, Stephanie A
dc.contributor.author Hatch, Brody
dc.contributor.author Slootmaker, Chris
dc.contributor.author Conan, Anne
dc.contributor.author Knobel, Darryn Leslie
dc.contributor.author Nel, Louis Hendrik
dc.date.accessioned 2020-07-13T10:30:26Z
dc.date.available 2020-07-13T10:30:26Z
dc.date.issued 2019-05-22
dc.description.abstract We present a new modeling tool that can be used to maximize the impact of canine rabies management resources that are available at the local level. The model is accessible through a web-based interface that allows for flexibility in the management strategies that can be investigated. Rabies vaccination, sterilization, chemo-contraception, and euthanasia can be specified and limited to specific demographic groups. Additionally, we allowed for considerable complexity in the specification of management costs. In many areas, the costs of contacting additional dogs increases as management effort increases, and this can have important strategic implications. We illustrated the application of the model by examining several alternative management strategies in an area of Mpumalanga Province, South Africa. Our results based on this dog population suggested that puppies should be vaccinated and sterilization would not be optimal if the spatial extent of management is not large (and perhaps not even then). Furthermore, given a sufficient budget, it was evident that vaccination campaigns should be repeated annually. en_ZA
dc.description.department Biochemistry en_ZA
dc.description.department Genetics en_ZA
dc.description.department Microbiology and Plant Pathology en_ZA
dc.description.department Veterinary Tropical Diseases en_ZA
dc.description.librarian hj2020 en_ZA
dc.description.sponsorship The intramural research program of the U.S. Department of Agriculture and UBS Optimus Foundation. en_ZA
dc.description.uri http://www.plosntds.org en_ZA
dc.identifier.citation Anderson, A., Kotzé, J., Shwiff, S.A. et al. A bioeconomic model for the optimization of local canine rabies control. PLoS Neglected Tropical Diseases 2019, 13(5): e0007377. https://DOI.org/10.1371/journal.pntd.0007377. en_ZA
dc.identifier.issn 1935-2727 (print)
dc.identifier.issn 1935-2735 (online)
dc.identifier.other 10.1371/journal.pntd.0007377
dc.identifier.uri http://hdl.handle.net/2263/75168
dc.language.iso en en_ZA
dc.publisher Public Library of Science en_ZA
dc.rights © 2019 by Author (s). This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 public domain dedication. en_ZA
dc.subject Optimization en_ZA
dc.subject Canine rabies en_ZA
dc.subject Mpumalanga province, South Africa en_ZA
dc.subject Management en_ZA
dc.subject Dogs (Canis familiaris) en_ZA
dc.title A bioeconomic model for the optimization of local canine rabies control en_ZA
dc.type Article en_ZA


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