Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe

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dc.contributor.advisor Crafford, Jan Ernst
dc.contributor.coadvisor Maritz-Olivier, Christine
dc.contributor.postgraduate Spargo, Reverend Moregood
dc.date.accessioned 2019-07-08T09:46:35Z
dc.date.available 2019-07-08T09:46:35Z
dc.date.created 2019/04/04
dc.date.issued 2018
dc.description Dissertation (MSc)--University of Pretoria, 2018.
dc.description.abstract Cattle ticks from the genus Rhipicephalus are hematophagous ectoparasites of great veterinary and economic importance. Currently, the main method for managing ticks and tick-borne diseases is the application of chemical acaricides. Development of resistance to these acaricides however poses a threat to the livestock sector globally, including Zimbabwe. Surveillance for acaricide resistance is essential for controlling tick populations via early intervention with an active compound to which there is no resistance in the field. In this study the allele frequencies that occur in genes linked to pyrethroid and amitraz resistance, namely the voltage-gated sodium channel and the octopamine/tyramine receptor were investigated. Specific nucleotide polymorphisms (SNPs) of Rhipicephalus spp in these genes were analysed from 18 communal dip tanks in the eastern parts of Zimbabwe. No SNPs were identified in the domain II region of the voltage-gated sodium channel gene associated with pyrethroid resistance. Resistant alleles associated with amitraz resistance in both R. decoloratus and R. microplus tick populations were observed. The level of acaricide resistance was subsequently calculated and solutions for improved acaricide resistance control are discussed.
dc.description.availability Unrestricted
dc.description.degree MSc
dc.description.department Veterinary Tropical Diseases
dc.identifier.citation Spargo, RM 2018, Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe, MSc Dissertation, University of Pretoria, Pretoria, viewed yymmdd <http://hdl.handle.net/2263/70495>
dc.identifier.other A2019
dc.identifier.uri http://hdl.handle.net/2263/70495
dc.language.iso en
dc.publisher University of Pretoria
dc.rights © 2019 University of Pretoria. All rights reserved. The copyright in this work vests in the University of Pretoria. No part of this work may be reproduced or transmitted in any form or by any means, without the prior written permission of the University of Pretoria.
dc.subject UCTD
dc.title Allele frequencies of acaricide resistance-associated specific nucleotide polymorphisms in Rhipicephalus microplus and Rhipicephalus decoloratus in Manicaland Zimbabwe
dc.type Dissertation


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