Asthma treatment in children : a pragmatic approach

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dc.contributor.author Masekela, Refiloe
dc.contributor.author Jeevarathnum, A.C.
dc.contributor.author Kling, S.
dc.contributor.author Gray, T.C.
dc.contributor.author Morrison, J.
dc.contributor.author Vanker, A.
dc.contributor.author Puterman, A.S.
dc.contributor.author Rhode, D.
dc.contributor.author Zollner, E.W.
dc.contributor.author De Waal, P.
dc.contributor.author Manjra, Ahmed I.
dc.contributor.author Levin, M.
dc.contributor.author Zar, Heather J.
dc.contributor.author Green, Robin J.
dc.contributor.author Kritzinger, F.E.
dc.date.accessioned 2018-11-29T04:50:09Z
dc.date.available 2018-11-29T04:50:09Z
dc.date.issued 2018-08
dc.description.abstract BACKGROUND. Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, with airway reversibility. Management of chronic inflammation with anti-asthma medication improves asthma control and quality of life. OBJECTIVES. To provide an evidence-based approach for chronic asthma management in young children and adolescents and provide guidance on the use of new asthma drugs in children. METHODS. The South African Childhood Asthma Working Group (SACAWG) convened in January 2017. The asthma treatment task group reviewed the available scientific literature and international asthma treatment guidelines. The evidence was then graded according to the Grades of Recommendation Assessment, Development and Evaluation (GRADE) system and recommendations were made based on scientific evidence and local context. Asthma management recommendations were made for children ˂6 years of age and older children and adolescents, as well as for stepping up and stepping down of therapy. This review does not include biologics or novel asthma drugs, which are covered in another CME article in this edition of SAMJ. CONCLUSIONS. To ensure good response, treatment and adherence, type of medication, device and checking of technique are all critical. Stepping up of therapy should be done only after ensuring good adherence and technique. Once therapeutic response is achieved, medication administration has to be stepped down to improve ease of use and avoid unnecessary side-effects. en_ZA
dc.description.department Paediatrics and Child Health en_ZA
dc.description.librarian am2018 en_ZA
dc.description.sponsorship SACAWG conducted a workshop that received an unconditional educational grant from the Allergy Society of South Africa – funded by Novartis. en_ZA
dc.description.uri http://www.samj.org.za en_ZA
dc.identifier.citation Masekela, R., Jeevanathrum, A., Kling, S. et al. 2018, 'Asthma treatment in children : a pragmatic approach', South African Medical Journal, vol. 108, no. 8, pp. 612-618. en_ZA
dc.identifier.issn 0256-9574 (print)
dc.identifier.issn 2078-5135 (online)
dc.identifier.other 10.7196/SAMJ.2018.v108i8.13164
dc.identifier.uri http://hdl.handle.net/2263/67391
dc.language.iso en en_ZA
dc.publisher Health and Medical Publishing Group en_ZA
dc.rights © 2018, South African Medical Association. This article is licensed under a Creative Commons Attribution-NonCommercial Works License (CC BY-NC 3.0). en_ZA
dc.subject Asthma en_ZA
dc.subject Chronic inflammation en_ZA
dc.subject Randomized controlled trial en_ZA
dc.subject Dose inhaled budesonide en_ZA
dc.subject Leukotriene receptor antagonist en_ZA
dc.subject Seasonal allergic rhinitis en_ZA
dc.subject Mild persistent asthma en_ZA
dc.subject Childhood asthma en_ZA
dc.subject Montelukast en_ZA
dc.subject Corticosteroids en_ZA
dc.subject South African Childhood Asthma Working Group (SACAWG) en_ZA
dc.subject Grades of recommendation assessment, development and evaluation (GRADE) en_ZA
dc.title Asthma treatment in children : a pragmatic approach en_ZA
dc.type Article en_ZA


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