The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum

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dc.contributor.author Soma-Pillay, Priya
dc.contributor.author Pillay, R.
dc.contributor.author Wong, T.Y.
dc.contributor.author Makin, J.D. (Jennifer Dianne)
dc.contributor.author Pattinson, Robert Clive
dc.date.accessioned 2018-04-20T10:54:59Z
dc.date.available 2018-04-20T10:54:59Z
dc.date.issued 2018-09
dc.description.abstract BACKGROUND : The retinal microcirculation provides a unique view of microvessel structure by means of non-invasive, retinal image analysis. The aim of the study was to compare the retinal vessel caliber at delivery and one-year post-partum between women who have had pre-eclampsia during pregnancy to a normotensive control group. METHODS : Digital photos of the eye were taken at delivery and one-year post-partum. Retinal vessels were analysed and summarised as the corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent. RESULTS : The corrected central retinal arteriolar equivalent and corrected central retinal venular equivalent were significantly lower in the pre-eclamptic group compared to the control group both at delivery and one-year post-partum (p < 0.001). CONCLUSION : Retinal artery and venular caliber changes that occur during pregnancies affected by pre-eclampsia persist for up to one-year post-partum. These changes may reflect a permanent, long-term microvascular dysfunction and may be useful as a biomarker of future vascular risk. en_ZA
dc.description.department Obstetrics and Gynaecology en_ZA
dc.description.librarian hj2018 en_ZA
dc.description.uri http://journals.sagepub.com/home/obm en_ZA
dc.identifier.citation Soma-Pillay, P., Pillay, R., Wong, T.Y. et al. 2018, 'The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum', Obstetric Medicine, vol. 11, no. 3, pp. 116-120. en_ZA
dc.identifier.issn 1753-495X (print)
dc.identifier.issn 1753-4968 (online)
dc.identifier.other 10.1177/1753495X17745727
dc.identifier.uri http://hdl.handle.net/2263/64670
dc.language.iso en en_ZA
dc.publisher Sage en_ZA
dc.rights © The Author(s) 2018 en_ZA
dc.subject Retinal microvascular calibre en_ZA
dc.subject Pre-eclampsia en_ZA
dc.subject Hypertension en_ZA
dc.title The effect of pre-eclampsia on retinal microvascular caliber at delivery and post-partum en_ZA
dc.type Postprint Article en_ZA


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