dc.contributor.author |
Pihl, Tina H.
|
|
dc.contributor.author |
Scheepers, Elrien
|
|
dc.contributor.author |
Sanz, Macarena
|
|
dc.contributor.author |
Goddard, Amelia
|
|
dc.contributor.author |
Page, Patrick
|
|
dc.contributor.author |
Toft, Nils
|
|
dc.contributor.author |
Kjelgaard-Hansen, Mads
|
|
dc.contributor.author |
Andersen, Pia H.
|
|
dc.contributor.author |
Jacobsen, Stine
|
|
dc.date.accessioned |
2017-09-20T05:18:42Z |
|
dc.date.issued |
2016-10 |
|
dc.description.abstract |
OBJECTIVE : To investigate the diagnostic potential of the concentrations of acute-phase proteins serum amyloid A (SAA), haptoglobin (Hp), and fibrinogen in blood and peritoneal fluid (PF) for differentiating horses with inflammatory colic (entero-colitis and peritonitis) from those with surgical colic. DESIGN : Prospective observational multicenter study. SETTING : Two university referral hospitals. ANIMALS : Horses referred for severe acute abdominal pain to Hospital 1 (n = 148) or Hospital 2 (n = 78). INTERVENTION : Blood and PF samples collected at admission were used for acute-phase protein concentration measurement. MEASUREMENTS AND MAIN RESULTS : Blood and PF samples collected at admission were used for acute-phase protein concentration measurement. CONCLUSIONS : Evaluation of SAA in serum improved the ability to differentiate horses with acute inflammatory colic requiring medical treatment from horses with colic requiring surgery, as it allowed an additional 4% of horses to be correctly classified into medical and surgical cases. Improved differentiation of these 2 groups of horses with colic may minimize the risk of unnecessary or delayed surgery. |
en_ZA |
dc.description.department |
Companion Animal Clinical Studies |
en_ZA |
dc.description.embargo |
2017-09-30 |
|
dc.description.librarian |
hj2017 |
en_ZA |
dc.description.sponsorship |
A Danish Government PhD grant and by the University of Pretoria from the Department of Companion Animal Clinical Studies Research Fund and the Faculty of Veterinary Science Research Fund. Additional funding was provided by the Danish funds, The Danish Horse Levy Fund, and The Kustos Foundation of 1881. |
en_ZA |
dc.description.uri |
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1476-4431 |
en_ZA |
dc.identifier.citation |
Pihl, T.H., Scheepers, E., Sanz, M., Goddard, A., Page, P., Toft, N., Kjelgaard-Hansen, M., Andersen, P.H. & Jacobsen, S. 2016, 'Acute-phase proteins as diagnostic markers in horses with colic', Journal of Veterinary Emergency and Critical Care, vol. 26, no. 5, pp. 664-674. |
en_ZA |
dc.identifier.issn |
1479-3261 (print) |
|
dc.identifier.issn |
1476-4431 (online) |
|
dc.identifier.other |
10.1111/vec.12504 |
|
dc.identifier.uri |
http://hdl.handle.net/2263/62480 |
|
dc.language.iso |
en |
en_ZA |
dc.publisher |
Wiley |
en_ZA |
dc.rights |
© 2016 Veterinary Emergency and Critical Care Society. This is the pre-peer reviewed version of the following article : 'Acute-phase proteins as diagnostic markers in horses with colic', Journal of Veterinary Emergency and Critical Care, vol. 26, no. 5, pp. 664-674, 2016, doi : 10.1111/vec.12504. The definite version is available at : http://onlinelibrary.wiley.comjournal/10.1111/(ISSN)1476-4431. |
en_ZA |
dc.subject |
Acute-phase proteins |
en_ZA |
dc.subject |
Peritoneal fluid (PF) |
en_ZA |
dc.subject |
Blood |
en_ZA |
dc.subject |
Horse (Equus caballus) |
en_ZA |
dc.subject |
Fibrinogen |
en_ZA |
dc.subject |
Haptoglobin (Hp) |
en_ZA |
dc.subject |
Serum amyloid A (SAA) |
en_ZA |
dc.subject |
Colic |
en_ZA |
dc.subject |
Body temperature |
en_ZA |
dc.subject |
Area under the curve |
en_ZA |
dc.subject |
Biochemical marker |
en_ZA |
dc.subject |
White blood cell count |
en_ZA |
dc.subject |
Lactate |
en_ZA |
dc.subject |
Equine |
en_ZA |
dc.subject |
Diagnostic marker |
en_ZA |
dc.title |
Acute-phase proteins as diagnostic markers in horses with colic |
en_ZA |
dc.type |
Postprint Article |
en_ZA |