Perspectives on peripheral neuropathy as a consequence of metformin-induced vitamin B12 deficiency in T2DM

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dc.contributor.author Ahmed, Marwan Awad
dc.contributor.author Muntingh, George L.
dc.contributor.author Rheeder, Paul
dc.date.accessioned 2017-09-12T09:52:09Z
dc.date.available 2017-09-12T09:52:09Z
dc.date.issued 2017-08-27
dc.description.abstract Peripheral neuropathy (PN) is a primary complication of type 2 diabetes mellitus (T2DM) and a direct manifestation of vitamin B12 deficiency. Examining the effects of metformin use on PN status became imperative following clinical studies that showed the vitamin B12-lowering effect of the medication. The complexity of the topic and the inconsistency of the results warrant consideration of topic-specific perspectives for better understanding of the available evidence and more appropriate design of future studies. en_ZA
dc.description.department Internal Medicine en_ZA
dc.description.department Pharmacology en_ZA
dc.description.librarian am2017 en_ZA
dc.description.uri https://www.hindawi.com/journals/ije en_ZA
dc.identifier.citation Ahmed, M.A., Muntingh, G.L. & Rheeder, P. 2017, 'Perspectives on peripheral neuropathy as a consequence of metformin-induced vitamin B12 deficiency in T2DM', International Journal of Endocrinology, vol. 2017, art. no. 2452853, pp. 1-6. en_ZA
dc.identifier.issn 1687-8337 (print)
dc.identifier.issn 1687-8345 (online)
dc.identifier.other 10.1155/2017/2452853
dc.identifier.uri http://hdl.handle.net/2263/62241
dc.language.iso en en_ZA
dc.publisher Hindawi Publishing Corporation en_ZA
dc.rights © 2017 Marwan A. Ahmed et al. This is an open access article distributed under the Creative Commons Attribution License. en_ZA
dc.subject Peripheral neuropathy (PN) en_ZA
dc.subject Type 2 diabetes mellitus (T2DM) en_ZA
dc.subject Vitamin B12 deficiency en_ZA
dc.subject Hyperhomocysteinemia en_ZA
dc.subject Risk en_ZA
dc.subject Folate en_ZA
dc.subject Mellitus en_ZA
dc.subject Prevalence en_ZA
dc.subject Homocysteine en_ZA
dc.subject Racial differences en_ZA
dc.subject Cobalamin deficiency en_ZA
dc.title Perspectives on peripheral neuropathy as a consequence of metformin-induced vitamin B12 deficiency in T2DM en_ZA
dc.type Article en_ZA


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