The cardiac glycoside from Urginea rubella Baker. Part. I. Isolation and properties of rubellin

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dc.contributor.author Louw, P.G.J.
dc.contributor.editor De Kock, G.v.d.W.
dc.date.accessioned 2017-03-02T08:58:45Z
dc.date.available 2017-03-02T08:58:45Z
dc.date.created 2017
dc.date.issued 1949
dc.description The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. en_ZA
dc.description.abstract 1. The active cardiac principle of Urginea rubella Baker has been isolated. Analysis points to the empirical formula C₃₆H₁₈O₁₆. The name suggested for this compound is "rubellin". Rubellin melts at 261-3°C. with decomposition and has [α]27/D = 15.81°(MeOH). 2. Hydrolysis of rubellin yields a sugar and pro-rubillidin, having M.P. 267-8°C. (decomp.) and [α]20/D = 24°(MeOH). 3. Succinic acid was isolated in small yield from the plant. 4. The toxicity of rubellin towards white rats was determined by intraperitoneal injection, the L.D.50 being 0.692 mgm. per Kg. Dosed to rabbits per os, the toxicity of rubellin is about 10 mgm. per Kilogram rabbit. en_ZA
dc.identifier.citation Louw, PGJ 1949, 'The cardiac glycoside from Urginea rubella Baker. Part. I. Isolation and properties of rubellin’, Onderstepoort Journal of Veterinary Science and Animal Industry, vol. 22, no. 2, pp. 313-319. en_ZA
dc.identifier.issn 0330-2465
dc.identifier.uri http://hdl.handle.net/2263/59232
dc.language.iso en en_ZA
dc.publisher Pretoria : The Government Printer en_ZA
dc.rights © 1949 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). © 2017 University of Pretoria. Dept. of Library Services (digital). en_ZA
dc.subject Veterinary medicine en_ZA
dc.subject.lcsh Veterinary medicine -- South Africa
dc.title The cardiac glycoside from Urginea rubella Baker. Part. I. Isolation and properties of rubellin en_ZA
dc.type Article en_ZA


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