Reference intervals for selected serum biochemistry analytes in cheetahs (Acinonyx jubatus)

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dc.contributor.author Hudson-Lamb, Gavin Charles
dc.contributor.author Schoeman, Johan P.
dc.contributor.author Hooijberg, Emma Henriette
dc.contributor.author Heinrich, Sonja K.
dc.contributor.author Tordiffe, Adrian Stephen Wolferstan
dc.date.accessioned 2016-08-04T09:30:23Z
dc.date.available 2016-08-04T09:30:23Z
dc.date.issued 2016-02-26
dc.description.abstract Published haematologic and serum biochemistry reference intervals are very scarce for captive cheetahs and even more for free-ranging cheetahs. The current study was performed to establish reference intervals for selected serum biochemistry analytes in cheetahs. Baseline serum biochemistry analytes were analysed from 66 healthy Namibian cheetahs. Samples were collected from 30 captive cheetahs at the AfriCat Foundation and 36 free-ranging cheetahs from central Namibia. The effects of captivity-status, age, sex and haemolysis score on the tested serum analytes were investigated. The biochemistry analytes that were measured were sodium, potassium, magnesium, chloride, urea and creatinine. The 90% confidence interval of the reference limits was obtained using the non-parametric bootstrap method. Reference intervals were preferentially determined by the non-parametric method and were as follows: sodium (128 mmol/L – 166 mmol/L), potassium (3.9 mmol/L – 5.2 mmol/L), magnesium (0.8 mmol/L – 1.2 mmol/L), chloride (97 mmol/L – 130 mmol/L), urea (8.2 mmol/L – 25.1 mmol/L) and creatinine (88 μmol/L – 288 μmol/L). Reference intervals from the current study were compared with International Species Information System values for cheetahs and found to be narrower. Moreover, age, sex and haemolysis score had no significant effect on the serum analytes in this study. Separate reference intervals for captive and free-ranging cheetahs were also determined. Captive cheetahs had higher urea values, most likely due to dietary factors. This study is the first to establish reference intervals for serum biochemistry analytes in cheetahs according to international guidelines. These results can be used for future health and disease assessments in both captive and free- ranging cheetahs. en_ZA
dc.description.department Companion Animal Clinical Studies en_ZA
dc.description.librarian am2016 en_ZA
dc.description.sponsorship The South African Veterinary Foundation (SAVF), the Wildlife Group of the South African Veterinary Association (SAVA), the Messerli Foundation in Switzerland and the Research Committee of the University of Pretoria. en_ZA
dc.description.uri http://www.jsava.co.za en_ZA
dc.identifier.citation Hudson-Lamb, G.C., Schoeman, J.P., Hooijberg, E.H., Heinrich, S.K. & Tordiffe, A.S.W., 2016, ‘Reference intervals for selected serum biochemistry analytes in cheetahs (Acinonyx jubatus)’, Journal of the South African Veterinary Association 87(1), Art. #1316, 6 pages. http:// dx.DOI.org/ 10.4102/jsava.v87i1.1316. en_ZA
dc.identifier.issn 1019-9128 (print)
dc.identifier.issn 2224-9435 (online)
dc.identifier.other 10.4102/jsava.v87i1.1316
dc.identifier.uri http://hdl.handle.net/2263/56188
dc.language.iso en en_ZA
dc.publisher AOSIS OpenJournals en_ZA
dc.rights © 2016. The Authors. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. en_ZA
dc.subject AfriCat Foundation en_ZA
dc.subject Captivity-status en_ZA
dc.subject Biochemistry analytes en_ZA
dc.subject Cheetah en_ZA
dc.subject Acinonyx jubatus
dc.title Reference intervals for selected serum biochemistry analytes in cheetahs (Acinonyx jubatus) en_ZA
dc.type Article en_ZA


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