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dc.contributor.author | Procos, J.![]() |
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dc.contributor.author | Labuschagne, F.J.![]() |
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dc.contributor.author | Van der Walt, J.G.![]() |
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dc.contributor.editor | Bigalke, R.D. | |
dc.contributor.editor | Cameron, Colin McKenzie | |
dc.contributor.editor | Gilchrist, Frances M.C. | |
dc.contributor.editor | Morren, A.J. | |
dc.contributor.editor | Verster, Anna J.M. | |
dc.contributor.editor | Verwoerd, Daniel Wynand | |
dc.contributor.editor | Walker, Jane B. | |
dc.contributor.other | Steyn, P.J.J. | |
dc.date.accessioned | 2016-07-07T08:28:25Z | |
dc.date.available | 2016-07-07T08:28:25Z | |
dc.date.created | 2016 | |
dc.date.issued | 1980 | |
dc.description | The articles have been scanned in colour with a HP Scanjet 5590; 300dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format. | en_ZA |
dc.description.abstract | Glucose turnover parameters were obtained in fed and fasted wethers, ewes and pregnant ewes in their 2nd and 3rd trimesters, using a jugular bolus injection of D-glucose-2-³H. Fasting significantly (P<0,05) reduced glucose turnover (c. 40%) in both the wether and the non-pregnant ewe. A somewhat larger difference (c. 54%) between the fed and fasted ewes was found in their 3rd trimester of pregnancy due to an increase when fed (c. 29% higher turnover than in the non-pregnant ewe) rather than a decrease when fasted, since there was no statistical difference (P< 0, 1) between glucose turnover values of pregnant or non-pregnant fasted ewes. Glucose tolerance was estimated from an intrajugular glucose load (1 g/kg⁰'⁷⁵ body mass) in these 3 groups of sheep under both fed and fasted conditions, and the resulting insulin response was followed for 4 h after the injection. Fasting reduced the plasma clearance rate of glucose by c. 63% in both the wether and the nonpregnant ewe while the reduction was somewhat smaller (c. 51%) during the 2nd trimester of pregnancy. Only the pregnant ewe group showed a corresponding reduction in the resulting insulin response of 46% which was similar in magnitude to the diminished clearance, indicating that factors other than insulin are responsible for the reduced glucose clearance associated with fasting in the weather and non-pregnant ewe. Despite similar baseline plasma glucose values the glucose load appeared to distribute in a space that was significantly less than that found in all 3 groups of fed sheep when trace amounts were injected. | en_ZA |
dc.identifier.citation | Van der Walt, JG, Procos, J & Labuschagne, FJ 1980, 'Glucose turnover, tolerance and insulin response in wethers, ewes and pregnant ewes in the fed and fasted state’, Onderstepoort Journal of Veterinary Research, vol. 47, no. 3, pp. 173-178. | en_ZA |
dc.identifier.issn | 0330-2465 | |
dc.identifier.uri | http://hdl.handle.net/2263/54155 | |
dc.language.iso | en | en_ZA |
dc.publisher | Published by the Government Printer, Pretoria. | en_ZA |
dc.rights | ©1980 ARC - Onderstepoort and Faculty of Veterinary Science, University of Pretoria (original). ©2016 University of Pretoria Department of Library Services (digital). | en_ZA |
dc.subject | Veterinary medicine | en_ZA |
dc.subject.lcsh | Veterinary medicine -- South Africa | |
dc.title | Glucose turnover, tolerance and insulin response in wethers, ewes and pregnant ewes in the fed and fasted state | en_ZA |
dc.type | Article | en_ZA |