Abstract:
Post-weaning mortality has a major economic implication for pig producers. Post-weaning
stress is influenced by a number of factors, including the piglets inherent ability and
physiological mechanisms to adapt to the new environment. Various amino acids, including
threonine, tryptophan and glutamine, have been shown to have a positive effect on the immune
system. Higher inclusion levels than current commercial standards of threonine, tryptophan or
glutamine and different combinations of these, were mixed into a basal weaner diet to create
eight dietary treatments. 48 crossbred piglets (Landrace x Large White) were included in a 28
day growth trail shortly after wean, with six piglets per treatment. Body weight gain, feed intake
and feed conversion efficiency (FCE) were measured weekly. At the onset of the trial, piglets
were injected with a 10% ovine erythrocyte suspension as an immune challenge. Blood samples
from each piglet were collected at 7 day intervals to obtain antibody titre values against ovine
erythrocytes. In general, amino acid concentrations used in this study did not result in
significant differences (P>0.05) between treatments except for a significant decrease in both
body weight gain and FCE when higher concentrations of threonine were fed. However, higher
antibody values against sheep erythrocytes were noted in piglets when they received additional
threonine in their feed (P>0.05). The results of this trial were not conclusive, but indicated a
negative impact of high threonine levels on the production performance of the piglets, while
simultaneously improving the production of antibodies against foreign protein molecules,
which could support the health of piglets during the post-weaning period.