First report of blaIMP-14 on a plasmid harboring multiple drug resistance genes in Escherichia coli sequence type 131
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| dc.contributor.author | Stoesser, Nicole
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| dc.contributor.author | Sheppard, Anna E.
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| dc.contributor.author | Peirano, Gisele
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| dc.contributor.author | Sebra, Robert
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| dc.contributor.author | Lynch, Tarah
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| dc.contributor.author | Anson, Luke
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| dc.contributor.author | Kasarskis, Andrew
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| dc.contributor.author | Motyl, Mary R.
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| dc.contributor.author | Crook, Derrick W.
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| dc.contributor.author | Pitout, Johann D.D.
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| dc.date.accessioned | 2016-06-24T08:03:13Z | |
| dc.date.available | 2016-06-24T08:03:13Z | |
| dc.date.issued | 2016-08 | |
| dc.description.abstract | The blaIMP-14 carbapenem resistance gene has largely previously been observed in Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and sequencing of carbapenem-resistant E. coli, we identified an ST131 strain harboring blaIMP-14 within a class 1 integron, itself nested within a ~54kb multi-drug resistance region on an epidemic IncA/C2 plasmid. The emergence of blaIMP-14 in this context in the ST131 lineage is of potential clinical concern. | en_ZA |
| dc.description.department | Medical Microbiology | en_ZA |
| dc.description.librarian | hb2016 | en_ZA |
| dc.description.uri | http://aac.asm.org | en_ZA |
| dc.identifier.citation | Stoesser, N, Sheppard, AE, Peirano, G, Sebra, R, Lynch, T, Anson, L, Kasarskis, A, Motyl, MR, Crook, DW & Pitout, JDD 2016, 'First report of blaIMP-14 on a plasmid harboring multiple drug resistance genes in Escherichia coli sequence type 131', Antimicrobial Agents and Chemotherapy, vol. 60, no. 8, pp. 5068-5071. | en_ZA |
| dc.identifier.issn | 0066-4804 (print) | |
| dc.identifier.issn | 1098-6596 (online) | |
| dc.identifier.other | 10.1128/AAC.00840-16 | |
| dc.identifier.uri | http://hdl.handle.net/2263/53392 | |
| dc.language.iso | en | en_ZA |
| dc.publisher | American Society for Microbiology | en_ZA |
| dc.rights | © 2016 Stoesser et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license. | en_ZA |
| dc.subject | Pseudomonas aeruginosa | en_ZA |
| dc.subject | Acinetobacter spp. | en_ZA |
| dc.subject | Global surveillance | en_ZA |
| dc.title | First report of blaIMP-14 on a plasmid harboring multiple drug resistance genes in Escherichia coli sequence type 131 | en_ZA |
| dc.type | Article | en_ZA |
