Abstract:
To discuss the embryological basis, sequela and management of intraoral synechia, and to report on the incidence of this
condition at a facial cleft deformity clinic (FCDC), with specific attention to two rare cases of mucosal bands involving the floor
of the mouth and palate. Review of the literature and a retrospective analysis of FCDC and case report of two cases. During the
period of 30 years (1983–2013), the FCDC - University of Pretoria has managed in excess of 4000 cases. A review of the clinic
statistics revealed only six cases in which intraoral synechiae occurred. The rarity of this condition at the FCDC is in keeping
with the rare incidence in the international literature. Four syndromic cases were identified. Three cases were cleft palate lateral
synechia syndrome, and one was an orofacial digital syndrome. Two nonsyndromic cases were identified, and both cases involved
the floor of the mouth and palate. The attending physicians and surgeons should be aware of the most appropriate timing for
management of this condition, in order to avoid unwanted sequelae. Supportive care should be provided, and emergency airway
protocol should be available for all cases. A differential diagnosis should be considered which includes syndromic conditions.