The response of the pituitary-adrenal and pituitary-thyroidal axes to the plasma glucose perturbations in Babesia canis rossi babesiosis

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dc.contributor.author Schoeman, Johan P.
dc.contributor.author Herrtage, Michael E.
dc.date.accessioned 2008-05-06T08:43:42Z
dc.date.available 2008-05-06T08:43:42Z
dc.date.issued 2007-12
dc.description.abstract This prospective, cross-sectional, interventional study was designed to determine the association between the hormones of the pituitary-adrenal and pituitary-thyroid axes and other clinical parameters with the blood glucose perturbations in dogs with naturally occurring Babesia canis rossi babesiosis. Thirty-six dogs with canine babesiosis were studied. Blood samples were obtained from the jugular vein in each dog prior to treatment at admission to hospital and serum endogenous adrenocorticotrophic hormone(ACTH), pre-ACTH cortisol, thyroxine, free thyroxine and TSH concentrations were measured. Basal and post-ACTH serum cortisol concentrations were significantly higher in hypoglycaemic dogs, whereas body temperature, serum thyroxine and free thyroxine were significantly lower in hypoglycaemic dogs. Haematocrit was significantly lower in both hypo-and hyperglycaemic dogs compared with normoglycaemic dogs. Low blood glucose concentrations were significantly associated with high basal and post-ACTH cortisol concentrations and with low serum thyroxine and free thyroxine concentrations in dogs suffering from B. canis rossi babesiosis. en
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dc.identifier.citation Schoeman, JP & Herrtage, ME 2007, 'The response of the pituitary-adrenal and pituitary-thyroidal axes to the plasma glucose perturbations in Babesia canis rossi babesiosis', Journal of the South African Veterinary Association, vol. 78, no. 4, pp. 215-220. [http://www.journals.co.za/ej/ejour_savet.html] en
dc.identifier.issn 0038-2809
dc.identifier.other 7005814117
dc.identifier.other J-6765-2013
dc.identifier.uri http://hdl.handle.net/2263/5132
dc.language.iso en en
dc.publisher South African Veterinary Association en
dc.rights South African Veterinary Association en
dc.subject ACTH en
dc.subject Babesia canis rossi en
dc.subject Body temperature en
dc.subject Cortisol en
dc.subject Free thyroxine en
dc.subject Glucose en
dc.subject Post-ACTH cortisol en
dc.subject Thyroxine en
dc.subject TSH en
dc.subject Haematocrit en
dc.subject.lcsh Babesiosis en
dc.subject.lcsh Veterinary medicine -- Diagnosis en
dc.subject.lcsh Thyroxine en
dc.title The response of the pituitary-adrenal and pituitary-thyroidal axes to the plasma glucose perturbations in Babesia canis rossi babesiosis en
dc.type Article en


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