Browsing Research Articles (Otorhinolaryngology) by Type "Article"

Browsing Research Articles (Otorhinolaryngology) by Type "Article"

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  • AI and precision oncology in clinical cancer genomics : from prevention to targeted cancer therapies-an outcomes based patient care 
    Dlamini, Zodwa; Skepu, Amanda; Kim, Namkug; Mkhabele, Mahlori; Khanyile, Richard; Molefi, Thulo; Mbatha, Sikhumbuzo; Setlai, Botle; Mulaudzi, Thanyani Victor; Mabongo, Mzubanzi; Bida, Nndweleni Meshack; Kgoebane-Maseko, Minah; Mathabe, Kgomotso; Lockhat, Zarina I.; Kgokolo, C.M.; Chauke-Malinga, Nkhensani; Ramagaga, Serwalo; Hull, Rodney (Elsevier, 2022)
    Precision medicine is the personalization of medicine to suit a specific group of people or even an individual patient, based on genetic or molecular profiling. This can be done using genomic, transcriptomic, epigenomic ...
  • Allergic rhinitis : review of the diagnosis and management : South African Allergic Rhinitis Working Group 
    Richards, Guy A.; Gray, Claudia L.; De Waal, Pieter; Friedman, Ray; Hockman, Maurice; Karabus, Sarah J.; Lodder, Cornelia M.; Mabelane, Tshegofatso; Mosito, Sylvia M.; Nanan, Ashen; Peter, Jonny G.; Quitter, Traugott H.C.; Van den Berg, Sylvia; Van Niekerk, Andre; Vardas, Eftyhia; Feldman, Charles (AOSIS, 2023-10-30)
    BACKGROUND : Allergic rhinitis (AR) has a significant impact on the community as a whole with regard to quality of life and its relationship to allergic multi-morbidities. Appropriate diagnosis, treatment and review of ...
  • Allergy and dizziness 
    Hofmeyr, Louis Murray (Media 24, 2015-06)
    Although allergies and dizziness are very common, little is known of their co-existence and relationship to each other. Allergy associated dizziness (AAD) refers to vertigo and disequilibrium.
  • A bedside system for clinical grading of parotid gland enlargement 
    Tshifularo, Mashudu (Health and Medical Publishing Group, 2015-06)
    There are limited data on grading of parotid gland mass, and currently no bedside clinical grading system is available. Parotid enlargement is common in patients with HIV/AIDS, and the size of the gland can change depending ...
  • Chronic rhinitis in South Africa – more than just allergy! 
    Green, Robin J.; Hockman, M.; Friedman, R.; Van Niekerk, Andre; Feldman, Charles; Vardas, E.; Quitter, R.; Els, Carla; Van Bruwaene, L.; Nanan, A.; Peter, J.; Seedat, R.Y.; Levin, M.; Bateman, C.; Davis, G.; Davis, M.; Gill, M.; Gray, C.; Karabus, S.; Lewis, H.; Lodder, C.; Maharaj, S.; McDonald, M.; Moodley, T.; Mosito, K.; Motakef, S.; Parris, Denise; Pio, P.; Ramjettan, S. (Health and Medical Publishing Group, 2020-07)
    Chronic rhinitis is a troublesome condition for sufferers. It is tempting to label all patients with chronic nasal symptoms as having allergic rhinitis (AR), but many such patients have other causes of chronic rhinitis ...
  • Elucidation of repeat motifs R1- and R2-related TRIOBP variants in autosomal recessive nonsyndromic hearing loss DFNB28 among indigenous South African individuals 
    Kabahuma, Rosemary Ida; Schubert, Wolf-Dieter; Labuschagne, Christiaan; Yan, Denise; Pepper, Michael Sean; Liu, Xue-Zhong (Wiley Open Access, 2022-10)
    BACKGROUND : DFNB28, a recessively inherited nonsyndromic form of deafness in humans, is caused by mutations in the TRIOBP gene (MIM #609761) on chromosome 22q13. Its protein TRIOBP helps to tightly bundle F-actin filaments, ...
  • Grommets and swimmers ear 
    Tshifularo, Mashudu (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor and Francis Group, 2018-09)
    Acute otitis media (AOM) is one of the most common childhood illnesses. While many children experience sporadic AOM episode, an important group suffer from recurrent AOM (rAOM), defined as three or more episodes in six ...
  • Otolaryngological and head and neck manifestations in HIV-infected patients seen at Steve Biko Academic Hospital in Pretoria, South Africa 
    Tshifularo, Mashudu; Govender, L.; Monama, G. (Health and Medical Publishing Group, 2013-07)
    BACKGROUND. Sub-Saharan Africa has the highest incidence of HIV infection. According to recent census statistics, 5.6 million people in South Africa (SA) are HIV-positive, the highest number of infected individuals ...
  • Otosclerosis and TGF-β1 gene in black South Africans 
    Tshifularo, Mashudu; Joseph, Christopher A. (Health and Medical Publishing Group, 2008-09)
    Limited literature is available on the epidemiology and genetics of otosclerosis in South African blacks, among whom it is extremely rare. We undertook this study because we had documented and surgically confirmed cases ...
  • Spectrum of MYO7A mutations in an indigenous South African population further elucidates the nonsyndromic autosomal recessive phenotype of DFNB2 to include both homozygous and compound heterozygous mutations 
    Kabahuma, Rosemary Ida; Schubert, Wolf-Dieter; Labuschagne, Christiaan; Yan, Denise; Blanton, Susan Halloran; Pepper, Michael Sean; Liu, Xue Zhong (MDPI, 2021-02-15)
    MYO7A gene encodes unconventional myosin VIIA, which, when mutated, causes a phenotypic spectrum ranging from recessive hearing loss DFNB2 to deaf-blindness, Usher Type 1B (USH1B). MYO7A mutations are reported in nine DFNB2 ...
  • Transoral robotic surgery (TORS) in South Africa 
    Fagan, J.J.; Wetter, Julie; Joseph, Christopher A.; Donde, Bernard (Health and Medical Publishing Group, 2017-01)
    A series of two-page advertisements have appeared in the September and November 2016 issues of the SAMJ, entitled ‘da Vinci Transoral Robotic Surgery (TORS) is a minimally invasive alternative to open surgery and full-dose ...
  • Tympanoplasty success based on surgeon and patient-reported outcomes perspectives : a 10-year review in a tertiary center 
    Tshifularo, Mashudu (SpringerOpen, 2022-01-28)
    BACKGROUND : The latest international trends in healthcare put more emphasis on patients’ perspectives in reporting success in surgical procedures. A holistic approach in measuring surgical outcomes, defined as global ...