Experience in South Africa of combining bioanalysis and instrumental analysis of PCDD/Fs

De Vos, Jayne; Quinn, Laura; Roos, Claudine; Pieters, Rialet; Gorst-Allman, Peter; Rohwer, Egmont Richard; Giesy, John P.; Bouwman, Henk

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Experience in South Africa of combining bioanalysis and instrumental analysis of PCDD/Fs

De Vos, Jayne; Quinn, Laura; Roos, Claudine; Pieters, Rialet; Gorst-Allman, Peter; Rohwer, Egmont Richard; Giesy, John P.; Bouwman, Henk

URI: http://hdl.handle.net/2263/42476

Date: 2013-05

Abstract:

We outline the experiences and the challenges of optimizing two-dimensional gas chromatography coupled with time-of-flight mass spectrometry (GCxGC-TOF-MS) in conjunction with the H4IIE-luc bioassay for analyzing polychlorinated dibenzo-p-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) in the South African context. Investigating such alternative analytical methods can assist countries with developing economies to meet their obligations under the Stockholm Convention.

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