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UP Centre for Sustainable Malaria Control (UP CSMC): Recent submissions
Now showing items 61-80 of 108
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(American Chemical Society, 2021-01)Recent studies on 3,6-diphenylated imidazopyridazines have demonstrated impressive in vitro activity and in vivo efficacy in mouse models of malaria infection. Herein, we report the synthesis and antiplasmodium evaluation ...
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(American Chemical Society, 2021-09)Please read abstract in the article.
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(PLoS Neglected Tropical Diseases, 2021-10)BACKGROUND : Assessment of surveillance and response system functions focusing on notifiable diseases has widely been documented in literature. However, there is limited focus on diseases targeted for elimination or ...
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(BMC, 2021-10)BACKGROUND : Effective health information systems (HIS) are critical towards achieving timely response to preventive chemotherapy neglected tropical diseases (PC-NTDs) and their eventual elimination. Strengthened HIS enable ...
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(Taylor and Francis, 2021)Malaria remains a public health concern with vector control still the vital component of disease prevention, control, and elimination strategies. Recent years has seen a “stalling” in the progress made towards the reduction ...
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(MDPI Publishing, 2021-09-28)Poly(lactic acid) (PLA) is an attractive candidate for replacing petrochemical polymers because it is fully biodegradable. This study investigated the potential of PLA as a sustainable and environmentally friendly ...
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(MDPI, 2020-10-16)This study was carried out to assess individuals’ willingness to pay (WTP) for UZIMAX, a novel plant-based biopesticide developed for malaria vector control. The biopesticide is estimated to kill up to 100% of Anopheles ...
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(Health and Medical Publishing Group, 2020-11)The COVID-19 pandemic has strained healthcare delivery systems in a number of southern African countries. Despite this, it is imperative that malaria control and elimination activities continue, especially to reduce as ...
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(Wiley, 2020-12)Nanocomposite strands with mosquito repellent DEET or Icaridin incorporated in a poly(ethylene-co-vinyl acetate) (EVA) matrix, with either pyrogenic silica or an organoclay as a nanofiller, were prepared by a twin-screw ...
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(Elsevier, 2021-04)A comprehensive review of refractive index mixing rules of binary solutions is presented. All published mixing rules, with the exception of the Wiener mixing rule, can be reformulated into expressions with a linear dependence ...
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(American Chemical Society, 2021-04)A novel series of antimalarial benzimidazole derivatives incorporating phenolic Mannich base side chains at the C2 position, which possess dual asexual blood and sexual stage activities, is presented. Structure–activity ...
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Assessment of surveillance core and support functions regarding neglected tropical diseases in Kenya (BioMed Central, 2021-01)BACKGROUND : Effective surveillance and response systems are vital to achievement of disease control and elimination goals. Kenya adopted the revised guidelines of the integrated disease surveillance and response system ...
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(BioMed Central, 2021-02)BACKGROUND : Control of preventive chemotherapy-targeted neglected tropical diseases (PC-NTDs) relies on strengthened health systems. Efficient health information systems provide an impetus to achieving the sustainable ...
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(Public Library of Science, 2021-03)BACKGROUND : The revised integrated disease surveillance and response (IDSR) guidelines adopted by African member states in 2010 aimed at strengthening surveillance systems critical capacities. Milestones achieved through ...
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(Nature Publishing Group, 2021-01)Chemical matter is needed to target the divergent biology associated with the different life cycle stages of Plasmodium. Here, we report the parallel de novo screening of the Medicines for Malaria Venture (MMV) Pandemic ...
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(Frontiers Media, 2021-06)The rapid development of antimalarial resistance motivates the continued search for novel compounds with a mode of action (MoA) different to current antimalarials. Phenotypic screening has delivered thousands of promising ...
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(BMC, 2021-02)BACKGROUND : South Africa aims to eliminate malaria transmission by 2023. However, despite sustained vector control efforts and case management interventions, the Vhembe District remains a malaria transmission hotspot. To ...
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(BMC, 2021-04)BACKGROUND : The Plasmodium sexual gametocyte stages are the only transmissible form of the malaria parasite and are thus responsible for the continued transmission of the disease. Gametocytes undergo extensive functional ...
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(American Chemical Society, 2021-03)The continued emergence of resistance to front-line antimalarial treatments is of great concern. Therefore, new compounds that potentially have a novel target in various developmental stages of Plasmodium parasites are ...
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(Hindawi, 2020-12-04)BACKGROUND : Local villages in the Vhembe district of South Africa have experienced high malaria infection rates and a high variability of malaria case mortality rates over the past 20 years. *is research project sets out ...
Now showing items 61-80 of 108