• Exploring the modulatory influence on the antimalarial activity of amodiaquine using scaffold hybridisation with ferrocene integration 

  Mbaba, Mziyanda; Golding, Taryn M.; Omondi, Reinner O.; Mohunlal, Roxanne; Egan, Timothy J.; Reader, Janette; Birkholtz, Lyn-Marie; Smith, Gregory S. (Elsevier, 2024-05)

  Amodiaquine (AQ) is a potent antimalarial drug used in combination with artesunate as part of artemisinin-based combination therapies (ACTs) for malarial treatment. Due to the rising emergence of resistant malaria parasites, ...
• Community perceptions, acceptability, and the durability of house screening interventions against exposure to malaria vectors in Nyimba district, Zambia 

  Saili, Kochelani; De Jager, Christiaan; Masaninga, Freddie; Chisanga, Brian; Sinyolo, Andy; Chiwaula, Japhet; Chirwa, Jacob; Hamainza, Busiku; Chanda, Emmanuel; Bakyaita, Nathan N.; Mutero, Clifford Maina (BMC, 2024-01)

  BACKGOUND: House screening remains conspicuously absent in national malaria programs despite its recognition by the World Health Organization as a supplementary malaria vector-control intervention. This may be attributed, ...
• Anopheles rufipes implicated in malaria transmission both indoors and outdoors alongside Anopheles funestus and Anopheles arabiensis in rural south-east Zambia 

  Saili, Kochelani; De Jager, Christiaan; Sangoro, Onyango P.; Nkya, Theresia E.; Masaninga, Freddie; Mwenya, Mwansa; Sinyolo, Andy; Hamainza, Busiku; Chanda, Emmanuel; Fillinger, Ulrike; Mutero, Clifford Maina (BMC, 2023-03-16)

  BACKGROUND : The primary malaria vector-control interventions, indoor residual spraying and long-lasting insecticidal nets, are effective against indoor biting and resting mosquito species. Consequently, outdoor biting and ...
• Correlating the density and refractive index of ternary liquid mixtures 

  Dzingai, Pethile; Focke, Walter Wilhelm; Ramjee, Shatish; Khosa, Pretty; Nobunga, Ripfumelo A. (Springer, 2023-11)

  Some physical properties of ideal solutions, e.g. the molar volume and the molar refraction, vary linearly with composition. Others can be expressed, either as ratios or as products of two other properties which vary ...
• Species composition, seasonal abundance, and biting behavior of malaria vectors in rural Conhane Village, Southern Mozambique 

  Salome, Graca; Riddin, Megan A.; Braack, L.E.O. (MDPI, 2023-02-17)

  Malaria vector surveillance provides important data to inform the effective planning of vector control interventions at a local level. The aim of this study was to determine the species diversity and abundance, biting ...
• hERG, Plasmodium life cycle, and cross resistance profiling of new azabenzimidazole analogues of astemizole 

  Mambwe, Dickson; Coertzen, Dina; Leshabane, Meta Kgaogelo; Mulubwa, Mwila; Njoroge, Mathew; Gibhard, Liezl; Girling, Gareth; Wicht, Kathryn J.; Lee, Marcus C.S.; Wittlin, Sergio; Moreira, Diogo Rodrigo Magalhaes; Birkholtz, Lyn-Marie; Chibale, Kelly (American Chemical Society, 2024-03)

  Please read abstract in the article.
• Characterizing the thermal phase behaviour of fipronil polymorphs 

  Moyo, Dennis Simbarashe; Van der Merwe, Elizabet Margaretha; Rademeyer, Melanie; Malan, F.P. (Frederick); Atanasova, Maria T.; Mapossa, António Benjamim; Focke, Walter Wilhelm (Springer, 2023-07)

  This manuscript reports the investigation of the polymorphic behaviour of fipronil using a systematic comparison of the thermochemical and structural properties of different crystal forms obtained in this study as well as ...
• Maternal exposure to pyrethroid insecticides during pregnancy and respiratory allergy symptoms among children participating in the Venda Health Examination of Mothers, Babies and their Environment (VHEMBE) 

  Elsiwi, Basant; Eskenazi, Brenda; Bornman, Maria S. (Riana); Obida, Muvhulawa; Kim, Joanne; Moodie, Erica E.M.; Mann, Koren K.; Chevrier, Jonathan (Elsevier, 2024-02)

  BACKGROUND : Pyrethroid insecticides use for indoor residual spraying (IRS) in malaria-endemic areas results in high levels of exposure to local populations. Pyrethroids may cause asthma and respiratory allergies but ...
• The association between long-term DDT or DDE exposures and an altered sperm epigenome-a cross-sectional study of Greenlandic Inuit and South African VhaVenda men 

  Lismer, Ariane; Shao, Xiaojian; Dumargne, Marie-Charlotte; Lafleur, Christine; Lambrot, Romain; Chan, Donovan; Toft, Gunnar; Bonde, Jens Peter; Macfarlane, Amanda J.; Bornman, Maria S. (Riana); Aneck-Hahn, Natalie Hildegard; Patrick, Sean Mark; Bailey, Janice M.; De Jager, Christiaan; Dumeaux, Vanessa; Trasler, Jacquetta M.; Kimmins, Sarah (National Institute of Environmental Health Sciences, 2024-01)

  Please read abstract in the article.
• School and community driven dengue vector control and monitoring in Myanmar : study protocol for a cluster randomized controlled trial 

  Overgaard, Hans J.; Linn, Nay Yi Yi; Kyaw, Aye Mon Mon; Braack, L.E.O.; Tin, Myo Win; Bastien, Sheri; Velde, Fiona Vande; Echaubard, Pierre; Zaw, Win; Mukaka, Mavuto; Maude, Richard (Taylor and Francis, 2023-08)

  BACKGROUND : Dengue is the most common and widespread mosquito-borne arboviral disease globally estimated to cause >390 million infections and >20,000 deaths annually. There are no effective preventive drugs and the newly ...
• Machine learning approaches identify chemical features for stage-specific antimalarial compounds 

  Van Heerden, Ashleigh; Turon, Gemma; Duran-Frigola, Miquel; Pillay, Nelishia; Birkholtz, Lyn-Marie (American Chemical Society, 2023-11-07)

  Efficacy data from diverse chemical libraries, screened against the various stages of the malaria parasite Plasmodium falciparum, including asexual blood stage (ABS) parasites and transmissible gametocytes, serve as a ...
• Phytoconstituents from Turraea obtusifolia and their antiplasmodial activity 

  Mianda, Sephora Mutombo; Moyo, Phanankosi; Maboane, Suzan; Birkholtz, Lyn-Marie; Maharaj, Vinesh J. (Taylor and Francis, 2024)

  Please read abstract in the article.
• Alpha viruses detected in mosquitoes in the North-Eastern regions of South Africa, 2014 to 2018 

  Guarido, Milehna M.; Meno, Kgothatso Debra; Mendes, Adriano; Riddin, M.A. (Megan); MacIntyre, Caitlin; Manyana, Sontaga; Johnson, Todd; Schrama, Maarten; Gorsich, Erin E.; Brooke, Basil D.; Almeida, Antonio Paulo G.; Venter, Marietjie (MDPI, 2023-02-23)

  The prevalence and distribution of African alphaviruses such as chikungunya have increased in recent years. Therefore, a better understanding of the local distribution of alphaviruses in vectors across the African continent ...
• Geo-epidemiology of malaria incidence in the Vhembe District to guide targeted elimination strategies, South-Africa, 2015-2018 : a local resurgence 

  Dieng, Sokhna; Adebayo-Ojo, Temitope Christina; Kruger, Taneshka; Riddin, Megan A.; Trehard, Helene; Tumelero, Serena; Bendiane, Marc-Karim; De Jager, Christiaan; Patrick, Sean Mark; Bornman, Maria S. (Riana); Gaudart, Jean (Nature Research, 2023)

  In South Africa, the population at risk of malaria is 10% (around six million inhabitants) and concern only three provinces of which Limpopo Province is the most affected, particularly in Vhembe District. As the elimination ...
• Household living conditions and individual behaviours associated with malaria risk : a community-based survey in the Limpopo River Valley, 2020, South Africa 

  Patrick, Sean Mark; Bendiane, Marc-Karim; Kruger, Taneshka; Harris, Bernice Nerine; Riddin, Megan A.; Trehard, Helene; De Jager, Christiaan; Bornman, Maria S. (Riana); Gaudart, Jean (BMC, 2023-05)

  BACKGROUND : Over the past decade, implementation of multiple malaria control strategies in most countries has largely contributed to advance the global malaria elimination agenda. Nevertheless, in some regions, seasonal ...
• COVID-19 and the malaria elimination agenda in Africa : re-shifting the focus 

  Patrick, Sean Mark; Cox, Sarah N.; Guidera, Kathryn E.; Simon, Molly J.; Kruger, Taneshka; Bornman, Maria S. (Riana) (Taylor and Francis, 2022)

  The global Coronavirus disease 2019 (COVID-19) pandemic has resulted in public health, political, scientific and private sector response at an unprecedented scale. However, this shift in focus has caused widespread disruption ...
• Social acceptance of livestock-administered endectocides for malaria control in Vhembe District, Limpopo Province, South Africa 

  Makhanthisa, Takalani Irene; Braack, L.E.O.; Bornman, Maria S. (Riana); Lutermann, Heike (BMC, 2022-10)

  BACKGROUND : Malaria continues to be a leading cause of morbidity and mortality in Africa and conventional malaria control strategies, such as indoor residual spraying and insecticide-treated bed nets, have limited ...
• Making data map-worthy—enhancing routine malaria data to support surveillance and mapping of Plasmodium falciparum anti-malarial resistance in a pre-elimination sub-Saharan African setting : a molecular and spatiotemporal epidemiology study 

  Kagoro, Frank M.; Allen, Elizabeth; Mabuza, Aaron; Workman, Lesley; Magagula, Ray; Kok, Gerdalize; Davies, Craig; Malatje, Gillian; Guerin, Philippe J.; Dhorda, Mehul; Maude, Richard J.; Raman, Jaishree; Barnes, Karen I. (Springer, 2022-06)

  BACKGROUND : Independent emergence and spread of artemisinin-resistant Plasmodium falciparum malaria have recently been confirmed in Africa, with molecular markers associated with artemisinin resistance increasingly detected. ...
• Could a culturally and age-appropriate song contribute towards malaria prevention in primary school learners? 

  Anderson, Chad M.; Eloff, Irma F.; Kruger, Taneshka (BMC, 2022-04)

  BACKGROUND : Although it is a preventable disease, malaria continues to present one of the major global health challenges. The disease is especially deadly to children under the age of 5 years. This is partly due to the ...
• Mosquitoes larvicidal activity of Ocimum kilimandscharicum oil formulation under laboratory and field-simulated conditions 

  Ochola, John Bwire; Mutero, Clifford Maina; Marubu, Rose Muthoni; Haller, Barbara Frei; Hassanali, Ahmed; Lwande, Wilber (MDPI, 2022-02-16)

  Mosquitoes are vectors of many severe diseases, including malaria, yellow as well as dengue fever, and lymphatic filariasis. The use of synthetic chemical insecticides for mosquito control has been associated with ...

View more