dc.contributor.author |
Bosman, Edolene
|
|
dc.contributor.author |
Esterhuizen, Aletta Dorothea
|
|
dc.contributor.author |
Rodrigues, Frederico Antonio
|
|
dc.contributor.author |
Becker, Piet J.
|
|
dc.contributor.author |
Hoffmann, Willem Abraham
|
|
dc.date.accessioned |
2014-03-28T12:14:48Z |
|
dc.date.available |
2014-03-28T12:14:48Z |
|
dc.date.issued |
2013-02 |
|
dc.description.abstract |
The aim of this study was to investigate the prevalence of hyperinsulinaemia in a group of normozoospermic donors and the influence of insulin levels on in vitro fertilisation (IVF) outcome. Fasting insulin and 2 h post-eating insulin levels were determined for a group of thirty-four sperm donors. They were divided into three groups according to their insulin profiles. The association between insulin levels and embryo quality was determined in a clinical study for the different groups. The prevalence of raised insulin in the donor group was 44% with a 95% confidence interval of 27.2% and 62.1%. Donors with normal insulin levels produced more good quality blastocysts in the IVF programme
than those with abnormal insulin levels. These differences were not
statistically significant (P = 0.8638). Embryo quality in an IVF programme may be influenced by male insulin levels. The role of insulin in male fertility needs to be investigated. |
en_US |
dc.description.librarian |
hb2014 |
en_US |
dc.description.librarian |
ay2014 |
|
dc.description.uri |
http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1439-0272 |
en_US |
dc.identifier.citation |
Bosman, E, Esterhuizen, AD, Rodrigues, FA, Becker, PJ & Hoffmann, WA 2013, 'Prevalence of hyperinsulinaemia among normozoospermic donors at Medfem Clinic, South Africa', Andrologia, vol. 45, no. 1, pp. 18-25. |
en_US |
dc.identifier.issn |
0303-4569 (print) |
|
dc.identifier.issn |
1439-0272 (online) |
|
dc.identifier.other |
10.1111/j.1439-0272.2012.01303.x |
|
dc.identifier.uri |
http://hdl.handle.net/2263/37209 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
Wiley-Blackwell |
en_US |
dc.rights |
© 2012 Blackwell Verlag GmbH.The definite version is available at : http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1439-0272 |
en_US |
dc.subject |
Embryo quality |
en_US |
dc.subject |
Fasting insulin |
en_US |
dc.subject |
Hyperinsulinaemia |
en_US |
dc.subject |
Two hour post-eating insulin |
en_US |
dc.subject.lcsh |
Fertility -- Endocrine aspects |
en |
dc.title |
Prevalence of hyperinsulinaemia among normozoospermic donors at Medfem Clinic, South Africa |
en_US |
dc.type |
Postprint Article |
en_US |