Prevalence of hyperinsulinaemia among normozoospermic donors at Medfem Clinic, South Africa

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dc.contributor.author Bosman, Edolene
dc.contributor.author Esterhuizen, Aletta Dorothea
dc.contributor.author Rodrigues, Frederico Antonio
dc.contributor.author Becker, Piet J.
dc.contributor.author Hoffmann, Willem Abraham
dc.date.accessioned 2014-03-28T12:14:48Z
dc.date.available 2014-03-28T12:14:48Z
dc.date.issued 2013-02
dc.description.abstract The aim of this study was to investigate the prevalence of hyperinsulinaemia in a group of normozoospermic donors and the influence of insulin levels on in vitro fertilisation (IVF) outcome. Fasting insulin and 2 h post-eating insulin levels were determined for a group of thirty-four sperm donors. They were divided into three groups according to their insulin profiles. The association between insulin levels and embryo quality was determined in a clinical study for the different groups. The prevalence of raised insulin in the donor group was 44% with a 95% confidence interval of 27.2% and 62.1%. Donors with normal insulin levels produced more good quality blastocysts in the IVF programme than those with abnormal insulin levels. These differences were not statistically significant (P = 0.8638). Embryo quality in an IVF programme may be influenced by male insulin levels. The role of insulin in male fertility needs to be investigated. en_US
dc.description.librarian hb2014 en_US
dc.description.librarian ay2014
dc.description.uri http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1439-0272 en_US
dc.identifier.citation Bosman, E, Esterhuizen, AD, Rodrigues, FA, Becker, PJ & Hoffmann, WA 2013, 'Prevalence of hyperinsulinaemia among normozoospermic donors at Medfem Clinic, South Africa', Andrologia, vol. 45, no. 1, pp. 18-25. en_US
dc.identifier.issn 0303-4569 (print)
dc.identifier.issn 1439-0272 (online)
dc.identifier.other 10.1111/j.1439-0272.2012.01303.x
dc.identifier.uri http://hdl.handle.net/2263/37209
dc.language.iso en en_US
dc.publisher Wiley-Blackwell en_US
dc.rights © 2012 Blackwell Verlag GmbH.The definite version is available at : http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1439-0272 en_US
dc.subject Embryo quality en_US
dc.subject Fasting insulin en_US
dc.subject Hyperinsulinaemia en_US
dc.subject Two hour post-eating insulin en_US
dc.subject.lcsh Fertility -- Endocrine aspects en
dc.title Prevalence of hyperinsulinaemia among normozoospermic donors at Medfem Clinic, South Africa en_US
dc.type Postprint Article en_US


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