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Browsing Natural and Agricultural Sciences by Subject "(Bis)thiourea"
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Verlinden, Bianca K.; Niemand, Jandeli; Snyman, Janette; Sharma, Shirv K.; Beattie, Ross J.; Woster, Partick M.; Birkholtz, Lyn-Marie
(American Chemical Society, 2011-10)
A series of alkylated (bis)urea and (bis)thiourea polyamine analogues were synthesized
and screened for antimalarial activity against chloroquine-sensitive and -resistant strains of Plasmodium
falciparum in vitro. All ...
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Verlinden, Bianca K.; De Beer, Marna; Pachaiyappan, Boobalan; Besaans, Ethan Wade; Anday, Warren A.; Reader, Janette; Niemand, Jandeli; Van Biljon, Riette Andele; Guy, Kiplin; Egan, Timothy; Woster, Patrick M.; Birkholtz, Lyn-Marie
(Elsevier, 2015-08)
A new series of potent potent aryl/alkylated (bis)urea- and (bis)thiourea polyamine analogues were synthesized
and evaluated in vitro for their antiplasmodial activity. Altering the carbon backbone and terminal
substituents ...