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Equine Research Centre: Recent submissions

  • Quantitative risk assessment for African horse sickness in live horses exported from South Africa 
    Sergeant, Evan S.; Grewar, John Duncan; Weyer, Camilla Theresa; Guthrie, Alan John (Public Library of Science, 2016-03-17)
    African horse sickness (AHS) is a severe, often fatal, arbovirus infection of horses, transmitted by Culicoides spp. midges. AHS occurs in most of sub-Saharan Africa and is a significant impediment to export of live ...
  • African horse sickness 
    Zientara, S.; Weyer, Camilla Theresa; Lecollinet, S. (International Office of Epizootics, 2015)
    African horse sickness (AHS) is a devastating disease of equids caused by an arthropod-borne virus belonging to the Reoviridae family, genus Orbivirus. It is considered a major health threat for horses in endemic areas ...
  • Fenced and fragmented : conservation value of managed metapopulations 
    Miller, Susan M.; Harper, Cindy Kim; Bloomer, Paulette; Hofmeyr, Jennifer; Funston, Paul J. (Public Library of Science, 2015-12-23)
    Population fragmentation is threatening biodiversity worldwide. Species that once roamed vast areas are increasingly being conserved in small, isolated areas. Modern management approaches must adapt to ensure the continued ...
  • The selection of a standard STR panel for DNA profiling of the African elephant (Loxodonta africana) in Kenya 
    Kinuthia, Julius; Harper, Cindy Kim; Muya, Shadrack; Kimwele, Charles; Alakonya, Amos; Muigai, Anne; Gakuya, Francis; Mwaniki, Mercy; Gatebe, Erastus (SpringerOpen Journal, 2015-06)
    The African elephant (Loxodonta africana) population in Kenya is declining at an alarming rate due to habitat destruction, human-elephant conflicts and the current escalation of poaching for ivory. This study established a ...
  • Equine encephalosis in Thoroughbred foals on a South African stud farm 
    Grewar, John Duncan; Thompson, P.N. (Peter N.); Lourens, Carina W.; Guthrie, Alan John (AOSIS OpenJournals, 2015-09-30)
    Thoroughbred foal body temperature data were collected from shortly after birth until shortly after weaning during the 2007/2008 season on a stud farm in the Western Cape Province of South Africa. Equine encephalosis ...
  • Epidemiology and reproductive outcomes of EHV-1 abortion epizootics in unvaccinated thoroughbred mares in South Africa 
    Schulman, M.L. (Martin); Becker, A.; Van der Merwe, B.D.; Guthrie, Alan John; Stout, T.A.E. (Tom) (Wiley, 2015-03)
    REASONS FOR PERFORMING STUDY : EHV-1 is one of the most common causes of infectious abortion in mares. Analyzing the demography of outbreaks and detailing subsequent reproductive performance of affected mares will assist ...
  • Serological response of foals to polyvalent and monovalent live-attenuated African horse sickness virus vaccines 
    Crafford, Jan Ernst; Lourens, Carina W.; Smit, T.K.; Gardner, Ian A.; MacLachlan, N.J. (James); Guthrie, Alan John (Elsevier, 2014-06)
    African horse sickness (AHS) is typically a highly fatal disease in susceptible horses and vaccinationis currently used to prevent the occurrence of disease in endemic areas. Similarly, vaccination has beencentral to the ...
  • The occurrence of Culicoides species, the vectors of arboviruses, at selected trap sites in Zimbabwe 
    Gordon, Stuart J.G.; Bolwell, Charlotte; Rogers, Chris; Musuka, Godfrey; Kelly, Patrick; Labuschagne, Karien; Guthrie, Alan John; Denison, Eric; Mellor, Philip S.; Hamblin, Christopher (AOSIS OpenJournals, 2015-05-29)
    A study of the distribution of Culicoides species was conducted by establishing 12 light trap sites over five rainy seasons between 1998 and 2003 covering all the geo-climatic natural regions of Zimbabwe. In total, 279 ...
  • Development of a real time polymerase chain reaction assay for equine encephalosis virus 
    Rathogwa, Ntungufhadzeni Maclaughlin; Quan, Melvyn; Smit, J.Q.; Lourens C.; Guthrie, Alan John; Van Vuuren, Moritz (Elsevier, 2014-01)
    Equine encephalosis virus (EEV) is the cause of equine encephalosis. The disease is similar to mild forms of African horse sickness (AHS) and the two diseases are easily confused. Laboratory identification and serotyping ...
  • Rapid growth rates of lion (Panthera leo) populations in small, fenced reserves in South Africa : a management dilemma 
    Miller, Susan M.; Funston, Paul J.; San, E. Do Linh (Southern African Wildlife Management Association, 2014-04)
    Managers of reintroduced lion (Panthera leo) populations in small reserves (<1000 km2) in South Africa are challenged by high rates of population increase and how best to control them.We combined data from 14 small, ...
  • The carrier prevalence of severe combined immunodeficiency, lavender foal syndrome and cerebellar abiotrophy in Arabian horses in South Africa 
    Tarr, Carolynne Jane; Thompson, P.N. (Peter N.); Guthrie, Alan John; Harper, Cindy Kim (Wiley, 2014-07)
    REASONS FOR PERFORMING STUDY : The carrier prevalence of severe combined immunodeficiency (SCID), lavender foal syndrome (LFS) and cerebellar abiotrophy (CA) in Arabian foals in South Africawas determined in order to ...
  • Evaluation of microsatellite markers for populations studies and forensic identification of African lions (Panthera leo) 
    Miller, Susan M.; Harper, Cindy Kim; Bloomer, Paulette; Hofmeyr, Jennifer; Funston, Paul J. (Oxford University Press, 2014-11)
    The South African lion (Panthera leo) population is highly fragmented. One third of its wild lions occur in small (<1000 km2) reserves. These lions were reintroduced from other areas of the species’ historical range. ...
  • Cyclic neutropenia in a basset hound 
    Koster, Liza Sally; Harper, Cindy Kim; Goddard, Amelia (BMJ Publishing Group, 2015)
    A 6 month old, male basset hound was referred for intermittent malaise, and pyrexia that repeated every 10-11 days. Sequential blood counts and bone marrow aspirates demonstrated severe neutropaenia and increased myeloid ...
  • Exercise-induced pulmonary haemorrhage impairs racing performance in thoroughbred racehorses 
    Morley, Paul S.; Bromberek, J.L.; Saulez, Montague Newton; Hinchcliff, Kenneth W.; Guthrie, Alan John (Wiley, 2015-05)
    REASONS FOR PERFORMING STUDY : Exercise-induced pulmonary haemorrhage (EIPH) occurs commonly in Thoroughbred racehorses worldwide. While EIPH is believed to be an important cause of impaired performance in these horses, ...
  • Diagnostic accuracy of a duplex real-time reverse transcription quantitative PCR assay for detection of African horse sickness virus 
    Guthrie, Alan John; MacLachlan, N.J. (James); Joone, Christopher; Lourens, Carina W.; Weyer, Camilla Theresa; Quan, Melvyn; Monyai, Mpho S.; Gardner, Ian A. (Elsevier, 2013)
    Blood samples collected from 503 suspect cases of African horse sickness (AHS) and another 503 from uninfected, unvaccinated South African horses, as well as 98 samples from horses from an AHS free country, were tested ...
  • African horse sickness in naturally infected, immunised horses 
    Weyer, Camilla Theresa; Quan, Melvyn; Joone, Christopher; Lourens, Carina W.; MacLachlan, N.J. (James); Guthrie, Alan John (Wiley-Blackwell, 2013-01)
    To determine whether subclinical cases, together with clinical cases, of African horse sickness (AHS) occur in immunised horses in field conditions, whole blood samples were collected and rectal temperatures recorded ...
  • The 2011 outbreak of African horse sickness in the African horse sickness controlled area in South Africa 
    Grewar, John Duncan; Weyer, Camilla Theresa; Guthrie, Alan John; Koen, Pieter; Davey, Sewellyn; Quan, Melvyn; Visser, Dawid; Rossouw, Esthea; Buhrmann, Gary (OpenJournals Publishing, 2013-11-15)
    African horse sickness (AHS) is a controlled animal disease in South Africa, and as a result of the high mortality rates experienced, outbreaks in the AHS controlled area in the Western Cape Province have a significant ...
  • Occurrence of African horse sickness in a domestic dog without apparent ingestion of horse meat 
    Van Sittert, Sybrand J.; Drew, Tessa M.; Kotze, Johann L.; Strydom, Tom; Weyer, Camilla Theresa; Guthrie, Alan John (OpenJournals Publishing, 2013-09-13)
    This is the first case of African horse sickness (AHS) in a dog where there was no apparent ingestion of horse meat. Significantly, the dog was part of a colony that resides in a Good Clinical Practice and Good Laboratory ...
  • Prediction of the optimal time for insemination using frozen-thawed semen in a multi-sire insemination trial in bitches 
    Steckler, Daniela; Nothling, Johan Oliviette; Harper, Cindy Kim (Elsevier, 2013-11)
    The aims of the study were to determine which of Days 5, 6 or 7 after the blood plasma progesterone concentration (PPC) of bitches first reached 6–9 nmol/L (Day 0) yield the highest fertility and whether day of insemination ...
  • The tiger genome and comparative analysis with lion and snow leopard genomes 
    Cho, Yun Sung; Hu, Li; Hou, Haolong; Lee, Hang; Xu, Jiaohui; Kwon, Soowhan; Oh, Sukhun; Kim, Hak-Min; Jho, Sungwoong; Kim, Sangsoo; Shin, Young-Ah; Kim, Byung Chul; Kim, Hyunmin; Kim, Chang-uk; Luo, Shu-Jin; Johnson, Warren E.; Koepfli, Klaus-Peter; Schmidt-Küntzel, Anne; Turner, Jason A.; Marker, Laurie; Harper, Cindy Kim; Miller, Susan M.; Jacobs, Wilhelm; Bertola, Laura D.; Kim, Tae Hyung; Lee, Sunghoon; Zhou, Qian; Jung, Hyun-Ju; Xu, Xiao; Gadhvi, Priyvrat; Xu, Pengwei; Xiong, Yingqi; Luo, Yadan; Pan, Shengkai; Gou, Caiyun; Chu, Xiuhui; Zhang, Jilin; Liu, Sanyang; He, Jing; Chen, Ying; Yang, Linfeng; Yang, Yulan; He, Jiaju; Liu, Sha; Wang, Junyi; Kim, Chul Hong; Kwak, Hwanjong; Kim, Jong-Soo; Hwang, Seungwoo; Ko, Junsu; Kim, Chang-Bae; Kim, Sangtae; Bayarlkhagva, Damdin; Paek, Woon Kee; Kim, Seong-Jin; O’Brien, Stephen J.; Wang, Jun; Bhak, Jong (Nature Publishing Group, 2013-09)
    Tigers and their close relatives (Panthera) are some of the world’s most endangered species. Here we report the de novo assembly of an Amur tiger whole-genome sequence as well as the genomic sequences of a white Bengal ...