• The effect of aspirin and lipopolysaccharide binding protein on hypercoagulability induced by lipopolysaccharide 

  Sibanda, Sthembile Valencia (University of Pretoria, 2019)

  Inflammation is a well-known underlying cause in many diseases. Chronic inflammation has a role in a host of common and often deadly diseases, including Alzheimer’s disease, rheumatoid arthritis, cancer, type 2 diabetes, ...
• The effects of whole body electromyostimulation exercise training on physical fitness in middle aged sedentary females 

  Burbidge, Michael (University of Pretoria, 2019)

  The purpose of this study was to determine the effects of whole-body electromyostimulation (WB-EMS) augmented calisthenic training on physique, maximum strength, balance and aerobic endurance and compare said effects to ...
• Diagnostic measures to inform training prescription to alter countermovement jump strategy and improve performance 

  Sangari, Darius B. (University of Pretoria, 2024-07-31)

  Jumping is a fundamental demonstration of lower-body power across various sports, where the ability to generate maximal force quickly is crucial. Central to optimising vertical jumping performance is the stretch-shorten ...
• The in vitro effects of a polyphenol epigallocatechin gallate on the cell viability, adhesion, and morphology of melanoma and endothelioma cells 

  Adigun, Aminat Opeyemi Iyanuoluwa (University of Pretoria, 2024-07-22)

  Adhesion molecules play a crucial role in the process of cancer cells adhering to and metastasising to secondary locations within the body. Adhesion molecules such as E-cadherin, play a crucial role in the adhesion and ...
• A description of the profile of paediatric brain tumours in a tertiary neurosurgery service 

  de Beer, Debbie (University of Pretoria, 2024-05-07)

  Background Central nervous system (CNS) tumours are the most common form of solid tumours in children, leading to significant mortality and morbidity. In developing countries, survival rates for children with CNS tumours ...
• Investigating the use of neurorehabilitation scales in paediatric neurosurgical patients at a tertiary academic hospital in Gauteng 

  Smit, Nicoleen (University of Pretoria, 2024-03-30)

  Introduction: Children with central nervous system disorders frequently display altered synaptic processes, discordant brain activity, delayed development, and reduced neuroplasticity. A major hallmark of neuroplasticity ...
• An ex vivo study on the hypercoagulability of brain cancer patients at an academic hospital by studying the morphological and viscoelastic properties of platelet-poor plasma 

  Rademeyer, Lilu (University of Pretoria, 2024-07-01)

  Cancer and its associated outcomes rank among the primary contributors to global mortality. Tumour cells are not only able to alter their cellular physiology to promote their own growth but can also disrupt the coagulation ...
• An investigation of somatosensory evoked potential responses during brain tumour surgery 

  Rasool, Muhammed Yusuf (University of Pretoria, 2024-07-02)

  Introduction: Intra-operative neurophysiological monitoring (IONM) is the use of electrophysiological tools to evaluate and monitor the functional status of the nervous system during surgery. The main aim of IONM is to ...
• The in vitro effects of diallyl trisulfide on osteoclast formation and function in RAW 264.7 murine macrophages 

  Mukozi, Maria Goretti Burungi Agnes (University of Pretoria, 2024-03)

  Osteoclasts are large multinucleated cells that resorb or degrade bone. Over-active osteoclasts result in fragile bones that fracture easily, causing bone degenerative disorders such as osteoporosis. Inhibiting osteoclast ...
• Investigating hypercoagulability in brain cancer patients by studying the viscoelastic and ultrastructural properties of whole blood 

  Seyfert, Zenobia Jacomine (University of Pretoria, 2024-04-02)

  Brain cancer is a condition with a relatively high rate of loss of life, regardless of patient demographics. The location and malignancy of the tumour are both determinants of this mortality rate, however there are ...
• Biomechanical investigations of coordination during initial acceleration in highly trained to world class sprinters 

  Donaldson, Byron John (University of Pretoria, 2023)

  Initial sprint acceleration is a complex and dynamic skill, requiring the application of large forces to propel the body forwards. Effective force application is achieved through the use of joint and segment rotations in ...
• A comparison of the risk profile for developing illness-related medical encounters in half- and ultra-marathon runners 

  Baker, Dean (University of Pretoria, 2023)

  Research comparing risk profiles for medical encounters in race entrants at distance running events is limited. The aim of this study was to determine and compare the risk profile for developing illness-related medical ...
• Between-session reliability of performance and asymmetry variables during lower limb strength tests and sport-specific tasks in netball players 

  Britz, Charne Beatrix (University of Pretoria, 2023)

  Title: Between-session reliability of performance and asymmetry variables during lower limb strength tests and sport-specific tasks in netball players Inter-limb asymmetry, the ratio that represents the performance ...
• Investigating clotting changes in patients from Steve Biko Academic Hospital with intracerebral haemorrhage by studying the viscoelastic and ultrastructural properties of whole blood. 

  Ferreira, Shene (University of Pretoria, 2023)

  Patients with intracerebral haemorrhage (ICH) have an increased risk of experiencing clotting changes when compared to healthy individuals, with recent research indicating that a bleeding event may enhance the prothrombotic ...
• Investigating the role of oxidative stress in apoptosis induced by a sulphamoylated estradiol analogue in breast cell lines 

  Lebelo, Maphuti Tebogo (University of Pretoria, 2020)

  2-Methoxyestradiol (2ME), a 17β-estradiol metabolite, exerts anticancer properties however, the compound was found to possess low bioavailability. This resulted in the in silico-design of 2ME analogues with a sulphamoyl ...
• Investigating lipopolysaccharide-induced inflammation in Sprague-Dawley rats on liver function with specific focus on coagulation factor production 

  Rathebe, Karabo (University of Pretoria, 2023)

  Neurodegenerative diseases, such as Parkinson’s disease (PD) and Alzheimer’s disease (AD), have long confounded the scientific and medical communities. The extensive research into these diseases, particularly AD has produced ...
• Association between head circumference and monocyte phenotype in neonates exposed and unexposed to HIV at Kalafong Provincial Tertiary Hospital 

  Sipsma, Iwan (University of Pretoria, 2023)

  It is well documented that children living with human immunodeficiency virus (HIV) do not perform as well as children not living with HIV on general cognitive tests, processing speed, and visual-spatial tasks, and are at ...
• Neopterin and neurophysiological measurements as markers of anxiety and stress 

  Cronje, Rouxzan (University of Pretoria, 2023)

  Background: Mental health is an increasing global crisis. It has large social, economic, and health costs, with stress and anxiety disorders accounting for a large portion of the impact. Biomarkers may help to improve the ...
• Investigation of the expression of pro-angiogenic markers in cutaneous tumours in vivo and in vitro 

  Nonxuba, Masibulele (University of Pretoria, 2023)

  Cutaneous tumours are common types of cancers that develop from the skin and account for 40% of the cases worldwide. In particular, melanomas and cutaneous haemangiomas are commonly occurring skin tumours that are characterised ...
• The epidemiology and associated risk factors for muscle strain injuries in endurance athletes 

  Kroon, Lize (University of Pretoria, 2023)

  Long-distance running continues to increase in popularity owing to its easy accessibility and people’s growing interest in disease prevention. Over the last 25 years, increasing participation in long-distance has been ...

View more