• Evaluation of molecular and serological assays for improved detection of orthobunyavirus infections in humans and animals in South Africa 

  Van der Walt, Miné (University of Pretoria, 2024)

  Over the last few decades, there has been a surge in occurrences of emerging and re-emerging infectious diseases, particularly those caused by viruses. To effectively anticipate and respond to future epidemics, rigorous ...
• Establishing a workflow for gastroenteritis virus surveillance, and norovirus whole genome characterisation by next-generation sequencing technologies 

  van Gaalen, Kerri-Anne (University of Pretoria, 2024-05-27)

  Acute gastroenteritis infection is a common illness seen around the world, with most cases being caused by viral pathogens such as rotavirus, norovirus, adenovirus, sapovirus, and astrovirus. Infection causes inflammation ...
• Establishment of serological assays to investigate the incidence of West Nile and Wesselsbron flavivirus infections in Africa 

  Lourens, Carla (University of Pretoria, 2023)

  The burden of WNV and association with neurological disease was identified through syndromic surveillance in animals and humans using available serological tools. WSLB virus was identified in two samples (an equine and ...
• Small-scale movements and foraging areas of Rousettus aegyptiacus in Limpopo Province, South Africa 

  Wood, Matthew Roger (University of Pretoria, 2023)

  Movement is an integral component within the animal kingdom as species respond to internal and external stimuli to ensure their survival. As animals move, they interact with the environment in different ways that help to ...
• Assessment of Bunyavirales activity and circulation in humans, livestock, and peri-domestic rodents in diverse ecologies in Kenya, 2020-2022 

  Omoga, Dorcus Caroline Achieng (University of Pretoria, 2023)

  Viruses in the order Bunyavirales are diverse and include zoonotic arthropod- and rodent-borne viruses that cause diseases ranging from mild febrile illnesses to haemorrhagic and/or encephalitis fevers and even death in ...
• Circulation, reassortment and transmission of Ngari and Bunyamwera viruses in Northen Kenya 

  Otieno, Odhiambo Collins (University of Pretoria, 2015)

  Kenya has experienced severe arboviral outbreaks of public health concern in the recent past, including yellow fever (YF), Crimean Congo hemorrhagic fever (CCHF), chikungunya, and Rift Valley fever (RVF) among others. Most ...
• Occurrence and diversity of tick-borne viruses in the pastoral eco-zone of Ijara District, North Eastern Province of Kenya 

  Lwande, Olivia Wesula (University of Pretoria, 2013-10)

  Most arbovirus isolations in East Africa have been recorded from mosquitoes but less information is available about tick-borne viruses including Crimean-Congo hemorrhagic fever virus (CCHFV), which is prevalent in Africa ...
• Assessment of selected environmental water samples in Kenya for the presence of clinically important enteric viruses 

  Kiulia, Nicholas Mukaria (University of Pretoria, 2013)

  Worldwide it is estimated that 1.1 billion people drink unsafe water and 1.7 million deaths are caused by drinking of unsafe water and poor sanitation. Enteric viruses are transmitted by the faecal-oral route and their ...
• The development and application of multiplex real-time reverse transcriptase polymerase chain reaction assays for the detection of enteric viruses on berry fruits and in water samples 

  De Ridder, Gabriel Adriaan (University of Pretoria, 2013)

  The transmission of enteric viruses by food, food products and water remains a wellrecognised, largely underestimated widespread public health problem. Outbreaks of gastroenteritis and hepatitis A due to the consumption ...
• Efficiency of glass wool adsorption-elution technique for the recovery of enteric viruses from water 

  Ruhanya, Vurayai (University of Pretoria, 2013)

  One of the major obstacles to human health relates to unsafe water and poor sanitation. Faecal contamination of source and drinking water introduces enteric pathogens which result in disease outbreaks. Therefore monitoring ...
• Molecular characterisation of hepatitis A virus strains from clinical and environmental sources in South Africa 

  Said, Rachida (University of Pretoria, 2013)

  Hepatitis A virus (HAV) is the most common cause of acute viral hepatitis worldwide. Hepatitis A virus is classified in the genus Hepatovirus of the family Picornaviridae. The virion has a 7.5 kb positive-sense single-stranded ...
• Early infant HIV diagnosis and characterization of HIV drug resistance in Gauteng, South Africa 

  Smit, Odette (University of Pretoria, 2021-01)

  Despite the high prevalence of the human immunodeficiency virus (HIV) in South African women of reproductive age, the South African (SA) Prevention of Mother-to-Child Transmission (PMTCT) programme has significantly reduced ...
• Molecular characterisation of human adenoviruses from environmental samples in Tshwane, Gauteng 

  Davids, Michaela (University of Pretoria, 2020)

  Human adenoviruses (HAdV) are non-enveloped viruses with an icosahedral capsid and a linear double-stranded DNA genome. These viruses belong to the family Adenoviridae and genus Mastadenovirus. An important property of the ...
• Identification and phylogenetic analysis of Aedes species (Diptera: Culicidae) and arboviruses associated with them across tropical and temperate regions of South Africa (2015-2018) 

  Guarido, Milehna M. (University of Pretoria, 2020)

  Emerging and re-emerging diseases have increased worldwide in incidence in the past decades. Of these emerging diseases 60.3% are caused by zoonotic pathogens of which 22.8% are arboviruses or arthropod borne viruses. ...
• Surveillance for rabies-related lyssaviruses in South African insectivorous bat species 

  Grobler, Colyn Stefan (University of Pretoria, 2021)

  Lyssaviruses are bullet shaped negative-sense RNA viruses that are all able to cause the fatal encephalitic disease known as rabies. The genus currently consists of 17 formally recognised viral species with one tentative ...
• Genetic assessment of infectious hepatitis A virus strains detected in selected water sources in Gauteng, South Africa 

  Rachida, Said (University of Pretoria, 2019-12)

  Hepatitis A is a vaccine preventable liver inflammation caused by the hepatitis A virus (HAV). Hepatitis A virus is the most common cause of acute viral hepatitis worldwide that is transmitted via the faecal-oral route ...
• Epidemiology and characterisation of enteric DNA viruses associated with gastroenteritis in children in selected regions of South Africa 

  Netshikweta, Rembuluwani (University of Pretoria, 2019)

  Acute gastroenteritis (AGE) is a global public health problem causing considerable morbidity and mortality among infants and children, especially in low-income settings. Viruses including group A rotaviruses (RVA), ...
• Assessing the risk of Transmission of Yellow Fever and Dengue viruses by Aedes (Stegomyia) mosquito populations in Northern Kenya 

  Chepkorir, Edith (University of Pretoria, 2019)

  East Africa has been experiencing an increase in the occurrence of emerging infectious diseases such as yellow fever (YF) and dengue (DEN). Increasing frequency of YF activity in East Africa constitutes a re-emergence that ...
• Surveillance of the rabies-related lyssavirus, Mokola, in small non-volant mammals in South Africa and Mozambique 

  McMahon, William Charles (University of Pretoria, 2020)

  Mokola virus (MOKV), a rabies-related lyssavirus, represents one of 17 recognized species within the Lyssavirus genus, all of which are capable of causing the fatal encephalitic rabies disease. MOKV is exclusively endemic ...
• The molecular epidemiology and diversity of gastroenteritis viruses in HIV-infected, -exposed and -unexposed children under the age of five years in Pretoria, South Africa 

  Rossouw, Esmari (University of Pretoria, 2020)

  Viruses are common causes of both endemic and epidemic gastroenteritis, infecting millions of people per year, with norovirus, rotavirus and adenovirus-F as the main causative agents, and sapovirus and astrovirus as ...

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