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Browsing Theses and Dissertations (Medical Microbiology) by Issue Date
Now showing items 1-20 of 40
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Evaluation of a radiometrically-determined regrowth model for the study of anti-tuberculosis drugs (University of Pretoria, 1999)Background: A post-exposure regrowth model utilizing the well-tried Bactec radiometric system, which would simulate in vivo situations at the site of invasive disease, was developed to measure drug activity against multiplying ...
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(University of Pretoria, 2004)Extended-spectrum beta-lactamases (ESBLs) in Pseudomonas aeruginosa tend to be geographically scattered, such as GES-2, which partially compromises the efficacy of imipenem. The G170N mutation, ascribed to a CC to AA base ...
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(University of Pretoria, 2005-09-22)Please read the abstract in the front section of this document
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(University of Pretoria, 2008-09-25)Extended-spectrum β-lactamases (ESBLs) constitute a major problem given their broad substrate specificity and ability to hydrolyse many of the extended-spectrum third-generation cephalosporins currently in use in hospital ...
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(University of Pretoria, 2010-03-01)Methicillin-resistant Staphylococcus aureus (MRSA) is a pandemic human pathogen accounting for most of health-care associated infections throughout the world. However, in recent years, a more virulent strain of MRSA has ...
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(University of Pretoria, 2010-05-13)The World Health Organization (WHO) estimated that eight million new cases of tuberculosis (TB) occur every year and that one-third of the world’s population is infected with Mycobacterium tuberculosis (M. tuberculosis). ...
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(University of Pretoria, 2012-08-08)Ureaplasma spp colonize the lower genital tract in many healthy men, yet can also cause urethritis and infertility. Since Ureaplasma spp are frequently isolated from the normal urogenital tract, it has been suggested ...
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(University of Pretoria, 2012-08-14)Klebsiella pneumoniae is an important nosocomial pathogen that has the potential to cause severe morbidity and mortality, particularly in intensive care units, as well as in medical and surgical wards. In recent years, ...
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(University of Pretoria, 2012-10-01)Multidrug-resistant (MDR) and extensively drug-resistant tuberculosis (XDR-TB) is a serious problem in South Africa. Standardised and accurate drug susceptibility testing for first-line and second-line anti-TB drugs are ...
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(University of Pretoria, 2012-12-14)Every year close to 9 million people contract tuberculosis (TB) and approximately 2 million die from the disease. The highest number of TB cases is in Asia while Africa has the highest incidence rates due to high rates ...
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(University of Pretoria, 2013)Antifungal drug resistance is a growing problem. Several mechanisms contribute to the development of resistance to antifungal agents. In South Africa, little is known about the antifungal susceptibility of local yeast ...
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Genetic relatedness of methicillin resistant Staphylococcus aureus isolates from Steve Biko hospital (University of Pretoria, 2013-04-18)Methicillin resistant Staphylococcus aureus (MRSA) causes severe infections in humans. An estimated two billion people carry S. aureus worldwide, of which fifty-three million harbour MRSA strains. The ability of MRSA to ...
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(University of Pretoria, 2013-04-18)Sexually transmitted infections (STIs) are a major cause of acute illnesses, infertility, long term disability and death with far reaching health, social and economic consequences. Trichomonas vaginalis is the causative ...
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(University of Pretoria, 2014)Tuberculosis (TB) remains a major global health problem. In 2012, an estimated 8.6 million people developed TB and 1.3 million died from the disease (including 320 000 deaths among HIV-positive people). All countries are ...
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(University of Pretoria, 2014)Bacterial vaginosis (BV) and genital mycoplasmas are infections of the reproductive tract that play important roles in maternal and foetal health. Genital mycoplasmas include Mycoplasma genitalium, M. hominis, Ureaplasma ...
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(University of Pretoria, 2014)Staphylococcus aureus (S. aureus) is one of the leading causes of human diseases in hospital and community settings. Methicillin resistant Staphylococcus aureus (MRSA) has emerged as a significant problem worldwide, resisting ...
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(University of Pretoria, 2015)The global control of tuberculosis (TB) is currently hindered by the low sensitivity of microscopy and the prolonged time-to-result of culture. Recent technical progress has improved both diagnostic accuracy and turnaround, ...
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(University of Pretoria, 2015)Genetic typing of Klebsiella pneumoniae is used for epidemiological referencing. In the clinical setting it can be useful in outbreak investigations, understanding transmission and managing hospital infections. Multi-drug ...
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(University of Pretoria, 2015)Tuberculosis (TB) is a major cause of death worldwide, especially in Asia and Africa. Genotyping methods such as insertion sequence 6110-restriction fragment length polymorphism (IS6110-RFLP), spoligotyping and mycobacterial ...
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(University of Pretoria, 2015)
Now showing items 1-20 of 40