We are excited to announce that the repository will soon undergo an upgrade, featuring a new look and feel along with several enhanced features to improve your experience. Please be on the lookout for further updates and announcements regarding the launch date. We appreciate your support and look forward to unveiling the improved platform soon.
Theses and Dissertations (Immunology)
Recent Submissions
-
Mashingaidze, Tsungai Vesta
(University of Pretoria, 2024)
Human immunodeficiency virus (HIV) infection has been observed to significantly impact both the immune system and haematopoiesis. Haematopoiesis is the regulated process of producing the cellular components of blood with ...
-
Hendricks, Candice Laverne
(University of Pretoria, 2024-06)
Umbilical cord blood (UCB) has been used for approximately 30 years as a source of haematopoietic stem and progenitor cells (HSPCs) for haematopoietic stem cell transplantation (HSCT). Advantages include less stringent ...
-
Mistry, Priyal
(University of Pretoria, 2023)
Human immunodeficiency virus (HIV-1) infection remains a significant global public health concern, particularly in sub-Saharan Africa where the majority of HIV infections are concentrated. HIV-1 is known to target the host ...
-
Mmakola, Khomotso Madimetsa Shelboy
(University of Pretoria, 2023)
ABSTRACT
BACKGROUND: Tuberculosis (TB) is a disease caused by the acid-fast bacterium, Mycobacterium tuberculosis (M. tuberculosis). It is currently the leading cause of morbidity and mortality worldwide due to a single ...
-
Pitere, Reabetswe
(University of Pretoria, 2023)
Obesity is a pandemic affecting both adults and children with an increasing annual prevalence. Adipogenesis, a process in which adipocyte precursors differentiate into mature adipocytes, is considered an important process ...
-
Sekalo, Lebogang
(University of Pretoria, 2023)
The present study was undertaken with the initial objective of investigating the effects of six primary anti-pseudomonal antibiotics, namely amikacin, cefepime, ciprofloxacin, meropenem, piperacillin and tazobactam, on the ...
-
Peta, Kimberly Thando
(University of Pretoria, 2023)
Breast cancer (BC) is the most prevalent cancer in females and the leading cause of cancer deaths. Treatment options include mastectomy, chemotherapy, and radiotherapy. While these treatments can improve 5-year survival ...
-
Mollentze, Jamie
(University of Pretoria, 2022)
The use of adipose-derived stromal/stem cells (ASCs) continues to increase in the field of regenerative medicine and other clinical applications. Adipose tissue can be collected in a less invasive procedure, when compared ...
-
Giles, Rachel
(University of Pretoria, 2022)
The aim of this project was to develop assays that will allow for high-throughput screening to monitor adipogenesis. Such an assay may be useful for the identification of potential drug targets during the process of ...
-
Malherbe, Glen Pierre
(University of Pretoria, 2014)
No abstract
-
Thaver, Veneesha
(University of Pretoria, 2010)
The major cause of HIV-related mortality in Sub-Saharan countries is pulmonary tuberculosis (TB), which is an escalating threat due to the emergence of multidrug resistant (MDR) and extremely multidrug resistant (XDR) TB. ...
-
Osman, Ayman Gassim Elamin
(University of Pretoria, 2020)
In his thesis, The roles of the potassium-uptake systems, Trk and Kdp, in the extracellular and intracellular growth of Mycobacterium tuberculosis, Mr Osman investigated the roles of the major potassium-uptake transporters ...
-
Mashele, Sizeka Aubrey
(University of Pretoria, 2020)
Background: The chemotherapy of tuberculosis (TB) patients is administered for a six to nine-
month period consisting of an intensive phase during the first two months with four primary anti-
TB drugs, rifampicin (RMP), ...
-
Mellet, Juanita
(University of Pretoria, 2019)
Umbilical cord blood (UCB) is a rich source of hematopoietic stem and progenitor cells (HSPCs). There are however limitations to using UCB as a regular source for hematopoietic stem cell transplantation (HSCT). The number ...
-
Wolmarans, Elize
(University of Pretoria, 2019)
Human adipose-derived stromal cells (hASCs) have gained increasing attention in the past decade as a potential cell therapeutic product. hASCs are classified as multipotent, fibroblast-like, plastic-adherent cells that can ...
-
Matapa, Kgashane Given
(University of Pretoria, 2019)
Streptococcus pneumoniae (the pneumococcus) is a Gram-positive bacterium that frequently colonises the nasopharynx of healthy humans. In susceptible hosts, especially children under 5 years with underdeveloped immune systems ...
-
Wickham, Catherine Heather
(University of Pretoria, 2019)
The human immunodeficiency virus (HIV) is the causative agent of acquired immune deficiency syndrome (AIDS), a condition characterized by depletion of CD4+ T cells and other immune system dysfunctions. Due to its widespread ...
-
Da Silva, Carina Corte-Real
(University of Pretoria, 2019)
Obesity is characterized by an excessive amount of body fat which can negatively affect health as it is a risk factor for various non-communicable diseases such as cardiovascular disease and diabetes, amongst others. A ...
-
Kallmeyer, Karlien
(University of Pretoria, 2019)
Adult mesenchymal stromal cells show promise therapeutically due to their multipotent differentiation capacity, immunomodulatory properties, paracrine signalling and ability to migrate to sites of injury. The potential use ...
-
Leijenaar, Stacey-Lee
(University of Pretoria, 2019-11-12)
Prostate cancer (PC) is the second most commonly occurring cancer in men, and the fourth most common commonly occurring cancer overall. Almost all PC begins in an androgen-dependent state with androgen deprivation therapy ...
View more