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Theses and Dissertations (Obstetrics and Gynaecology)
Recent Submissions
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(University of Pretoria, 2024-04-02)Background. Diabetes in pregnancy (DIP) is associated with short- and long-term adverse pregnancy outcomes for both mother and child. However, pregestational type 1 (T1DM) and type 2 (T2DM) are associated with more common ...
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(University of Pretoria, 2023)In this thesis, Development of a screening algorithm for the cervical cancer prevention programme in Botswana, the candidate utilised a new human papillomavirus (HPV) deoxyribonucleic acid (DNA) assay called Antila AmpFire ...
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(University of Pretoria, 2019)Introduction: Gestational diabetes mellitus (GDM) is a significant public health concern, due to its association with short- and long-term complications in both mothers and offspring. DNA methylation and single nucleotide ...
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(University of Pretoria, 2018)Introduction: Somatic cell nuclear transfer (SCNT) is the removal (enucleation) of chromosomes from a metaphase II oocyte, followed by the transfer and fusion of a donor somatic cell to the enucleated oocyte (cytoplast). ...
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(University of Pretoria, 2017)OBJECTIVES Maternal near-miss audits were initially introduced to evaluate the quality of obstetric care at the time of the event. One of the principle advantages of studying near-misses is that these women are able to ...
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(University of Pretoria, 2017)Abstract Introduction Knowledge about the oncologic status of pelvic lymph nodes forms an essential and integral part in the management of women with uterine cancer. Lymph node status is part of endometrial cancer ...
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(University of Pretoria, 2017)Globally, there is an alarming increase in the incidence of Type II diabetes mellitus (T2DM). It is well recognized that women who develop gestational diabetes (GDM) in their pregnancies are at increased risk of T2DM in ...
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(University of Pretoria, 2017)Pelvic floor dysfunction in the form of pelvic organ prolapse (POP) is a common gynaecological condition, especially in the elderly. Although the aetiology is poorly understood, several risk factors such as vaginal childbirth, ...
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(University of Pretoria, 2017)Introduction: The desire to have a biological child transcends race, religion and socio-economic status. However for those faced with infertility, the financial resources needed to conceive are often not available. Current ...
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(University of Pretoria, 2016)Objectives: Despite current comprehension of HPV epidemiology, the question of how HPV type distribution in the South African population differs from that in the rest of the world remains largely unanswered for both ...
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(University of Pretoria, 2015)Introduction: Intrauterine insemination (IUI) is frequently used as the first-line treatment for infertility, due to the relative simplicity and cost-effectiveness of the procedure. Even though, several sperm processing ...
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(University of Pretoria, 2013)Introduction: Cryopreservation of human sperm is considered a routine practice in assisted reproduction laboratories. Semen samples are mainly cryopreserved as a back-up for procedures, donor sperm, and validation of samples ...
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(University of Pretoria, 2013)Introduction International guidelines endorse the screening of patients for human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV) and Chlamydia trachomatis before assisted reproductive ...
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(University of Pretoria, 2013)The presence of pathogens in semen can compromise the outcome of assisted reproductive treatment, together with the possibility of the female partner or offspring becoming infected. This is cause for concern, especially ...
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(University of Pretoria, 2011-10-25)PROJECT ONE Introduction HPV is detected in about 99.7% of cervical cancers. However, the HPV type distribution in South African women is unknown. Objectives To determine HPV-type distribution among women with cervical ...
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The role of the tumour suppressor gene PTEN in the etiology of cancers of the female genital tract (University of Pretoria, 2011-10-24)The phosphorylation and dephosphorylation of the tyrosine amino-acids in proteins play an important role in the regulation of many cellular processes in all eukariotic organisms, including the regulation of cell cycle ...
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(University of Pretoria, 2008-06-02)Several studies have highlighted the possibility that radio-frequency electromagnetic fields (RF-EMF) used in mobile phone technology could influence DNA integrity of male germ cells as well as sperm motility. Current ...