• Electrochemical reduction of Formic acid using an earth abundant catalyst 

  Ndlangamandla, Simphiwe (University of Pretoria, 2019-11)

  Copper is one of the most useful electrocatalysts for electrochemically converting CO2 to hydrocarbons and alcohols. Unfortunately, copper suffers from a lack of selectivity and efficiency. Earth-abundant electrocatalysts ...
• The design, synthesis and biological evaluation of novel compounds against biomarkers of Alzheimer’s disease 

  Van Greunen, Divan Gerald (University of Pretoria, 2019-06)

  Alzheimer’s disease (AD) is the most common neurodegenerative disease accounting for an estimated 60 – 80 % of dementia cases. The disease affected 5.5 million Americans older than 65 years in 2018 alone, and this number ...
• Synthesis, characterization and applications of polymer based conjugate materials for infectious diseases of poverty 

  Tshweu, Lesego Lovius (University of Pretoria, 2018-12)

  The major disease burden for the majority of the world’s population is due to infectious diseases. The most prevalent are HIV/AIDS, tuberculosis, lower respiratory tract infections, diarrhoeal diseases and malaria. In ...
• Anti-inflammatory and anti-diabetic properties of plant extracts and compounds from Scabiosa columbaria and Sclerocarya birrea 

  Ezeofor, Chidinma Christiana (University of Pretoria, 2023)

  Given that South Africa is home to around 10% of all flowering plant species known to humans, the country is blessed with an abundance of natural resources. About 24,000 plant species have yet to be fully uncovered for the ...
• The electrochemical reduction of CO2 to value-added products 

  Klopper, Reinard (University of Pretoria, 2024-02-23)

  Carbon dioxide is the fourth most abundant gas in the atmosphere making up 0.035 %. Carbon dioxide prevents heat from escaping into the outer space and is used by plants to make oxygen. The levels of carbon dioxide have ...
• Chemical analysis and survey of mycotoxins in South African produced grains with emphasis on those produced by stenocarpella maydis in maize 

  Meyer, Johanna Christina (University of Pretoria, 2024-02-20)

  During the latter half of the previous century, new mycotoxins were discovered as secondary metabolites of fungi in major grains before harvest. The prevalence of these toxic compounds and the negative health effects caused ...
• Intermolecular bonding in water clusters from the molecular-wide and electron density-based (MOWED) perspective : a theoretical study 

  Zaaiman, Stéfan (University of Pretoria, 2023-12-14)

  Cooperativity is a strange phenomenon in water clusters, characterized by a non-linear decrease in the average electronic energy of a water molecule or hydrogen bond with an increase in cluster size. The main aim of this ...
• Porphyrin-based porous organic polymers enriched with Fe3O4  nanoparticles as electrosensors for the detection of endocrine disrupting chemicals in water 

  Berrange, Lu-Nita (University of Pretoria, 2023-11)

  Endocrine disrupting chemicals (EDCs) are commonly found in products such as pesticides, plastics, and pharmaceuticals. These chemicals are of significant concern due to their potential to disrupt the endocrine system, ...
• Development of analytical methods for N-nitrosamine disinfection byproducts in drinking water 

  Tyhali, Akhona (University of Pretoria, 2023-10-23)

  N-nitrosamines (NAs) are widely recognized as cancer-causing and genotoxic substances that emerge in water primarily as a result of chlorination or chloramination disinfection processes when nitrogen-containing compounds ...
• Evaluation of labelling mechanisms and analytical procedures for Ga-68 labelled peptides used in positron emission tomography 

  Marjanovic-Painter, Biljana (University of Pretoria, 2023)

  Nuclear Medicine imaging involves the monitoring of disease processes by using radioactive signals produced by radiopharmaceuticals (injected intravenously) to monitor the pharmacokinetic behaviour of compounds non-invasively ...
• Development of a natural product library using hyphenated techniques and evaluation of its constituents as potential anti-cancer agents 

  Mc Millan, Patrick Matthew (University of Pretoria, 2023)

  Worldwide, cancer is among the most common public health issues with an estimated death toll in 2020 of close to 10 million individuals. Although cancer treatments are continuously improving as the use of personalised ...
• Acid-mediated green synthesis and optimization of the calcium-terephthalate metal-organic framework derived from waste eggshells 

  Van Niekerk, Gizelle (University of Pretoria, 2023)

  Global plastic and food waste generation has climbed to unprecedented levels, inherently linked to exponential population growth since the 1950s accompanied by industrialization, urbanization and modernization. The reduction ...
• Synthesis, electronic structure and reactivity of rhodium(I) and iridium(I) bis(imino)acenaphthene complexes 

  Louw, Wynand Johannes (University of Pretoria, 2022)

  The bis(arylimino)acenaphthalene (BIAN) group of α-diimine compounds has shown promising electron sink behaviour and redox non-innocent activity as ligands to main group and transition metals. Here we present a series of ...
• Beneficiation of diamond mine residues for the synthesis of Mg containing compounds 

  Castleman, Barbara Ann (University of Pretoria, 2023)

  The aim of this study is to develop a process for the valorisation of diamond mine residues. This entailed a combination of thermochemical solid-solid reactions between the mine residues and ammonium sulphate, followed by ...
• The synthesis and release studies of polyethylene glycol-lumefantrine conjugates with varying length linkers 

  Govender, Thenesia (University of Pretoria, 2023)

  Malaria remains a global burden, specifically affecting developing countries in sub-Saharan Africa, East Asia and Oceania. To address the high mortality rates associated with severe malaria, researchers at the Council of ...
• Holistic synthesis of iron-based metal-organic frameworks using unconventional metal feedstock and polyethylene terephthalate derived organic linkers 

  Mthembu, Nqobile Themba (University of Pretoria, 2022)

  The high costs associated with the synthesis of Metal-organic frameworks (MOFs) owing to the expensive raw materials have significantly attributed to the lack of large-scale production of MOFs regardless of their appealing ...
• Novel air monitoring technologies for volatile and semi-volatile organic compounds for sustainable development 

  Geldenhuys, Genna-Leigh (University of Pretoria, 2023)

  Environmental protection and the search for cleaner, more sustainable fuels are two of the most important concerns modern society is facing. This research aims to determine whether a transition from fossil fuels to the use ...
• Development of primary reference gas mixtures for volatile organic compound monitoring in South Africa 

  Ntsasa, Napo Godwill (University of Pretoria, 2022)

  Direct monitoring of volatile organic compounds (VOCs) emitted from industrial sources and the monitoring of ambient levels thereof in the atmosphere, play an essential role in providing data for various legislative ...
• Chemical profiling, isolation, and characterization of bioactive compounds from Rhynchosia minima var prostrata and Phragmites mauritianus 

  Adewole, Adetola Henry (University of Pretoria, 2022)

  Indigenous medicine is a common form of healthcare in the rural parts of Africa, South Africa not excluded. Traditional healers have ethnomedicinal reports documented or passed from one generation to another by word of ...
• Characterization and isolation of anti-HIV and latency reversal agents for the development of a herbal mixture of Gnidia sericocephala, Senna italica, Sclerocarya birrea and Pentanisia prunelloides 

  Tembeni, Babalwa (University of Pretoria, 2022)

  Two non-daphnane diterpenoids were isolated as biomarkers and later identified using one and two dimensional nuclear magnetic resonance (1D and 2D NMR) as lasioerin and lasiocephalin. The preparative purification of the ...

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