Abstract:
HIV-salivary gland associated disease is a well accepted concept in the HIV-related literature. Parotid
swellings, especially in its cystic benign lymphoepithelial form, have been largely reported. Oral
mucoceles (ranulas) were also associated with HIV in some publications. The exact nature of this link
between mucoceles and HIV is still to be clarified. The mainstream treatment of most of parotid
pathologies and oral mucoceles remains surgical approach. Strong evidences do, however, exist about
lymphopithelial lesions of parotid glands that have been successfully treated with antiretroviral
drugs. We present a case of intraoral mucocele, coexisting with bilateral parotid gland
lymphoepithelial lesions, on a 2-year-old HIV-positive patient. Both parotid gland swellings and
the sublingual mucocele have completely regressed following antiretroviral therapy. No surgical
intervention was required. Conversely to benign lymphoepithelial lesions of parotid glands, the
regression of oral mucocele on HIV-positive patient, following antiretroviral drugs therapy appears to
be a rare phenomenon.
