Browsing Research Articles (Pharmacology) by Type "Article"

Browsing Research Articles (Pharmacology) by Type "Article"

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  • A 2021 update : approach to asthma management in adults 
    Schellack, Natalie; Truter, A.; Ntuli, P.N.; Mokwele, N.; Mogale, K.; Esterhuizen, A. (Medpharm Publications, 2021-08)
    Asthma is a chronic inflammatory disease that causes hyper-responsiveness of the bronchial tree, with reversible airflow obstruction. The condition places a significant burden on our healthcare system. Chronic asthma can ...
  • Acute non-specific low back pain in primary care 
    Outhoff, Kim (Medpharm, 2014)
    Acute non-specific low back pain, usually a result of muscle strains and ligament sprains from lifting, exercising or moving unexpectedly, is commonly encountered in primary care. At any given time, approximately one in ...
  • Additional considerations for gastro-oesophageal reflux disease 
    Marais, Andre (MedPharm Publications, 2016)
    Gastro-oesophageal reflux disease (GORD) is a common condition worldwide. It is characterised by numerous upper gastrointestinal tract symptoms, but patients mainly present with heartburn and regurgitation. Various causes ...
  • African herbal remedies with antioxidant activity : a potential resource base for wound treatment 
    Gulumian, Mary; Yahaya, Ewura Seidu; Steenkamp, Vanessa (Hindawi, 2018-11-22)
    The use of traditional herbal remedies as alternativemedicine plays an important role in Africa since it forms part of primary health care for treatment of various medical conditions, including wounds. Although physiological ...
  • Agomelatine : a review for general practitioners 
    Outhoff, Kim (South African Academy of Family Practice/Primary Care, 2012)
    Agomelatine is a novel melatonergic antidepressant that restores disrupted biological rhythms, essentially by resetting the circadian clock. Two different, non-monoaminergic, and possibly synergistic pathways, appear to ...
  • The allergic eye 
    Marais, Andre (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2016)
    Allergic conjunctivitis is a common condition encountered by the healthcare professional. Several factors have been implicated as possible causes and almost all involve an IgE mediated immune response. Symptoms may vary ...
  • Allergic rhinitis 
    Sommers, De K. (MedPharm Publications, 2015)
  • “Alpha-1, are you in? (C)harlie (O)scar (P)appa (D)elta, over!” 
    Muntingh, George L. (MedPharm Publications, 2016)
    Chronic obstructive pulmonary disease (COPD) is characterised by chronically poor air flow. Typically, it worsens over time. The main symptoms include shortness of breath, coughing and sputum production. Most people with ...
  • Alzheimers - or just senior moments? 
    Marais, Andre (Plus 50 Media (Pty) Ltd., 2015-05)
    The signs and symptoms of Alzheimer's disease differ from normal age-related changes. Declining memory starts from around 40, and it is normal to experience changes in memory as you grow older, but memory loss that disrupts ...
  • Alzheimer’s disease in family practice 
    Greeff, Oppel Bernhardt Wilhelm (OpenJournals, 2009-09)
    21 September 2009 is hailed as World Alzheimer's Day, creating awareness for the most common type of all the dementias. Senile dementia of the Alzheimer's type (SDAT) has a four to five year survival rate if a patient is ...
  • Anaemia in chronic kidney disease – a review 
    Kok, Elandre (Medpharm Publications, 2020)
    The management of anaemia in chronic kidney disease (CKD) patients is a complex, multifaceted process reliant on the administration of exogenous erythropoiesis stimulating agents (ESAs) and iron supplements to ensure the ...
  • Anaemia – a pale ale? 
    Muntingh, George L.; Viljoen, M. (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor and Francis Group, 2017)
    Despite some modest improvements described recently, anaemia remains a significant global public health concern affecting both developed and developing countries. It affects a quarter of the global population, including ...
  • Angiotensin converting enzyme inhibitors v. angiotensin receptor blockers in the management of hypertension : a funder's perspective 
    Makkink, Jaco L.; Greeff, Oppel Bernhardt Wilhelm (Health and Medical Publishing Group, 2014-04)
    BACKGROUND. Hypertension poses a huge financial risk to any funder/medical aid, including the risk-mitigating strategies provided by the managed care organisations that are required to manage patients with hypertension. ...
  • The anti-inflammatory properties of simvastatin can benefit statin-naïve rheumatoid arthritis patients with associated risks for cardiovascular disease 
    Komolafe, Ayoola Oluwakayode; Ally, Mahmood Moosa Tar Mahomed; Van Tonder, Jacob John; Greeff, Oppel Bernhardt Wilhelm (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor & Francis Group, 2015-01)
    The anti-inflammatory properties of statins are well documented. The aim of this study was to determine if statins may offer therapeutic benefits in rheumatoid arthritis (RA) patients that are also at risk for cardiovascular ...
  • Antibody prevalence to African swine fever virus, Mycobacterium bovis, foot-and-​mouth disease virus, Rift Valley fever virus, influenza A virus, and Brucella and Leptospira spp. in free-ranging warthog (Phacochoerus africanus) populations in South Africa 
    Neiffer, Donald; Hewlett, Jennie; Buss, Peter Erik; Rossouw, Leana; Hausler, Guy; DeKlerk-Lorist, Lin-Mari; Roos, Eduard; Olea-Popelka, Francisco; Lubisi, Baratang Alison; Heath, Livio; Miller, Michele (Wildlife Disease Association, 2020-01)
    The warthog (Phacochoerus africanus) can be used as a model for investigating disease transmission at the human, wildlife, and livestock interface. An omnivore and scavenger, a warthog moves freely between natural ecotypes, ...
  • Antidepressant-induced sexual dysfunction 
    Outhoff, Kim (OpenJournals, 2009-07)
    Depression and sexual dysfunction are both common in the general population. When they co-exist they have the potential to impact negatively on each other in a bidirectional manner. Medication used to treat depression may ...
  • Antimicrobial stewardship activities in public healthcare facilities in South Africa : a baseline for future direction 
    Engler, Deirdre; Meyer, Johanna Catharina; Schellack, Natalie; Kurdi, Amanj; Godman, Brian (MDPI, 2021-08-17)
    Antimicrobial resistance (AMR) is a growing problem worldwide, including South Africa, where an AMR National Strategy Framework was implemented to instigate antimicrobial stewardship programmes (ASPs) and improve antimicrobial ...
  • Antimicrobial therapeutic drug monitoring in critically ill adult patients : an international perspective on access, utilisation, and barriers 
    Williams, Paul G.; Cotta, Menino Osbert; Tabah, Alexis; Sandaradura, Indy; Kanji, Salmaan; Scheetz, Marc H.; Imani, Sahand; Elhadi, Muhammed; Pardos, Sònia L.; Schellack, Natalie; Sanches, Cristina; Timsit, Jean‑Francois; Xie, Jiao; Farkas, Andras; Wilks, Kathryn; Roberts, Jason A. (Elsevier, 2024-08)
    BACKGROUND: Therapeutic drug monitoring (TDM) is an effective method for individualising antimicrobial therapy in critically ill patients. The 2021 ADMIN-intensive care unit survey studied a wide range of intensive care ...
  • An appraisal of the regulatory policies governing the use of herbal traditional medicine 
    Netzer, Keren; Balmith, Marissa; Flepisi, Brian Thabile (TMR, 2021-10-26)
    The regulation of herbal traditional medicine (HTM) is of much importance as it ensures the safety, quality and efficacy thereof. However, there are variations in the regulation of HTM worldwide with some countries being ...
  • The art of prescribing trastuzumab for HER2-positive breast cancer 
    Outhoff, Kim (OpenJournals Publishing, 2011-03)
    The human epidermal growth factor receptor 2 (HER2) is overexpressed in HER2-positive breast cancer. This confers characteristics associated with an overall poor prognosis, with early metastases to major visceral sites and ...